Epigenetics in Psychiatry

Jacob Peedicayil, Dennis R. Grayson, Dimitrios Avramopoulos

Research output: Book/ReportBook

Abstract

Epigenetics in Psychiatry, Second Edition covers all major areas of psychiatry in which extensive epigenetic research has been performed, fully encompassing a diverse and maturing field, including drug addiction, bipolar disorder, epidemiology, cognitive disorders, and the uses of putative epigenetic-based psychotropic drugs. Uniquely, each chapter correlates epigenetics with relevant advances across genomics, transcriptomics, and proteomics. The book acts as a catalyst for further research in this growing area of psychiatry. This new edition has been fully revised to address recent advances in epigenetic understanding of psychiatric disorders, evoking data consortia (e.g., CommonMind, ATAC-seq), single cell analysis, and epigenome-wide association studies to empower new research. The book also examines epigenetic effects of the microbiome on psychiatric disorders, and the use of neuroimaging in studying the role of epigenetic mechanisms of gene expression. Ongoing advances in epigenetic therapy are explored in-depth.

Original languageEnglish (US)
PublisherElsevier
Number of pages816
ISBN (Electronic)9780128235775
DOIs
StatePublished - Jan 1 2021

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology

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