Epigenetic alterations in pancreatic cancer

Michael Ayars, Michael Goggins

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Pancreatic cancer remains one of the deadliest malignancies. In addition to genetic alterations a wide variety of epigenetic aberrations have been identified in pancreatic neoplasms some of which are thought to play an important role in neoplastic development and maintenance. Newer technologies are helping to better characterize cancer epigenomes. Efforts are underway to identify epigenetic alterations that would make optimal diagnostic markers and therapeutic targets. In this chapter, we discuss recent findings in the field of pancreatic cancer epigenetics and the implications they hold for future research.

Original languageEnglish (US)
Title of host publicationMolecular Genetics of Pancreatic Cancer
PublisherSpringer New York
Pages185-207
Number of pages23
Volume9781461465492
ISBN (Electronic)9781461465492
ISBN (Print)1461465486, 9781461465485
DOIs
StatePublished - Jan 1 2013

ASJC Scopus subject areas

  • Medicine(all)

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