Pancreatic cancer remains one of the deadliest malignancies. In addition to genetic alterations a wide variety of epigenetic aberrations have been identified in pancreatic neoplasms some of which are thought to play an important role in neoplastic development and maintenance. Newer technologies are helping to better characterize cancer epigenomes. Efforts are underway to identify epigenetic alterations that would make optimal diagnostic markers and therapeutic targets. In this chapter, we discuss recent findings in the field of pancreatic cancer epigenetics and the implications they hold for future research.
|Original language||English (US)|
|Title of host publication||Molecular Genetics of Pancreatic Cancer|
|Publisher||Springer New York|
|Number of pages||23|
|ISBN (Print)||1461465486, 9781461465485|
|State||Published - Jan 1 2013|
ASJC Scopus subject areas