Epidural spinal involvement of Erdheim-Chester disease causing myelopathy

Brian Y. Hwang, Ann Liu, Jason Kern, C. Rory Goodwin, Jean Paul Wolinsky, Atman Desai

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


We present a 25-year-old woman with Erdheim-Chester disease (ECD) presenting with progressive myelopathy from multiple compressive spinal epidural lesions who required cervicothoracic decompression and fusion, and summarize the literature on epidural spinal involvement of ECD. ECD is a rare non-Langerhans histiocytosis affecting multiple organ systems through infiltration and characteristically causing multifocal osteosclerosis. Central nervous system involvement, particularly of the spine, is rare.

Original languageEnglish (US)
Pages (from-to)1532-1536
Number of pages5
JournalJournal of Clinical Neuroscience
Issue number9
StatePublished - 2015


  • Epidural
  • Erdheim-Chester disease
  • Non-Langerhans histiocytosis
  • Spine

ASJC Scopus subject areas

  • Surgery
  • Neurology
  • Clinical Neurology
  • Physiology (medical)


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