Epidural spinal involvement of Erdheim-Chester disease causing myelopathy

Brian Y. Hwang, Ann Liu, Jason Kern, C. Rory Goodwin, Jean Paul Wolinsky, Atman Desai

Research output: Contribution to journalArticle

Abstract

We present a 25-year-old woman with Erdheim-Chester disease (ECD) presenting with progressive myelopathy from multiple compressive spinal epidural lesions who required cervicothoracic decompression and fusion, and summarize the literature on epidural spinal involvement of ECD. ECD is a rare non-Langerhans histiocytosis affecting multiple organ systems through infiltration and characteristically causing multifocal osteosclerosis. Central nervous system involvement, particularly of the spine, is rare.

Original languageEnglish (US)
Pages (from-to)1532-1536
Number of pages5
JournalJournal of Clinical Neuroscience
Volume22
Issue number9
DOIs
StatePublished - 2015

Fingerprint

Erdheim-Chester Disease
Spinal Cord Diseases
Osteosclerosis
Histiocytosis
Spinal Cord Compression
Decompression
Spine
Central Nervous System

Keywords

  • Epidural
  • Erdheim-Chester disease
  • Non-Langerhans histiocytosis
  • Spine

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Physiology (medical)

Cite this

Hwang, B. Y., Liu, A., Kern, J., Goodwin, C. R., Wolinsky, J. P., & Desai, A. (2015). Epidural spinal involvement of Erdheim-Chester disease causing myelopathy. Journal of Clinical Neuroscience, 22(9), 1532-1536. https://doi.org/10.1016/j.jocn.2015.04.004

Epidural spinal involvement of Erdheim-Chester disease causing myelopathy. / Hwang, Brian Y.; Liu, Ann; Kern, Jason; Goodwin, C. Rory; Wolinsky, Jean Paul; Desai, Atman.

In: Journal of Clinical Neuroscience, Vol. 22, No. 9, 2015, p. 1532-1536.

Research output: Contribution to journalArticle

Hwang, BY, Liu, A, Kern, J, Goodwin, CR, Wolinsky, JP & Desai, A 2015, 'Epidural spinal involvement of Erdheim-Chester disease causing myelopathy', Journal of Clinical Neuroscience, vol. 22, no. 9, pp. 1532-1536. https://doi.org/10.1016/j.jocn.2015.04.004
Hwang, Brian Y. ; Liu, Ann ; Kern, Jason ; Goodwin, C. Rory ; Wolinsky, Jean Paul ; Desai, Atman. / Epidural spinal involvement of Erdheim-Chester disease causing myelopathy. In: Journal of Clinical Neuroscience. 2015 ; Vol. 22, No. 9. pp. 1532-1536.
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