Epidural spinal compression as an initial presentation of Hodgkin lymphoma

Nancy Abu-Bonsrah; Akwasi Ofori Boah; C. Rory Goodwin; Tatianna Larman; Genevieve M. Crane; Daniel M. Sciubba

doi:10.1016/j.jocn.2015.10.026

Epidural spinal compression as an initial presentation of Hodgkin lymphoma

Nancy Abu-Bonsrah, Akwasi Ofori Boah, C. Rory Goodwin, Tatianna Larman, Genevieve M. Crane, Daniel M. Sciubba

School of Medicine

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Classical Hodgkin lymphoma (CHL) commonly arises in lymph nodes and initial presentation with extranodal disease is rare. We report a patient who presented with progressively worsening back pain, lower extremity weakness and numbness concerning for a myelopathic process of uncertain etiology. MRI revealed an epidural soft tissue mass with cord displacement, for which she underwent resection. Histological analysis of the surgical specimen demonstrated CHL. Further investigation revealed an anterior mediastinal mass, consistent with spread from a more typical location.

Original language	English (US)
Pages (from-to)	166-168
Number of pages	3
Journal	Journal of Clinical Neuroscience
Volume	26
DOIs	https://doi.org/10.1016/j.jocn.2015.10.026
State	Published - Apr 1 2016

Keywords

Epidural cord compression
Hodgkin lymphoma
Spine

ASJC Scopus subject areas

Surgery
Neurology
Clinical Neurology
Physiology (medical)

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10.1016/j.jocn.2015.10.026

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title = "Epidural spinal compression as an initial presentation of Hodgkin lymphoma",

abstract = "Classical Hodgkin lymphoma (CHL) commonly arises in lymph nodes and initial presentation with extranodal disease is rare. We report a patient who presented with progressively worsening back pain, lower extremity weakness and numbness concerning for a myelopathic process of uncertain etiology. MRI revealed an epidural soft tissue mass with cord displacement, for which she underwent resection. Histological analysis of the surgical specimen demonstrated CHL. Further investigation revealed an anterior mediastinal mass, consistent with spread from a more typical location.",

keywords = "Epidural cord compression, Hodgkin lymphoma, Spine",

author = "Nancy Abu-Bonsrah and Boah, {Akwasi Ofori} and Goodwin, {C. Rory} and Tatianna Larman and Crane, {Genevieve M.} and Sciubba, {Daniel M.}",

note = "Funding Information: C.R.G. is a UNCF Merck Postdoctoral Fellow and has received an award from the Burroughs Wellcome Fund. This article reflects the views of the author C.R.G. and should not be construed to represent the FDA{\textquoteright}s views or policies. D.S. is a consultant for DePuy, Medtronic, Orthofix, and Globus. The other authors declare that they have no financial or other conflicts of interest in relation to this research and its publication.",

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doi = "10.1016/j.jocn.2015.10.026",

language = "English (US)",

volume = "26",

pages = "166--168",

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T1 - Epidural spinal compression as an initial presentation of Hodgkin lymphoma

AU - Abu-Bonsrah, Nancy

AU - Boah, Akwasi Ofori

AU - Goodwin, C. Rory

AU - Larman, Tatianna

AU - Crane, Genevieve M.

AU - Sciubba, Daniel M.

N1 - Funding Information: C.R.G. is a UNCF Merck Postdoctoral Fellow and has received an award from the Burroughs Wellcome Fund. This article reflects the views of the author C.R.G. and should not be construed to represent the FDA’s views or policies. D.S. is a consultant for DePuy, Medtronic, Orthofix, and Globus. The other authors declare that they have no financial or other conflicts of interest in relation to this research and its publication.

PY - 2016/4/1

Y1 - 2016/4/1

N2 - Classical Hodgkin lymphoma (CHL) commonly arises in lymph nodes and initial presentation with extranodal disease is rare. We report a patient who presented with progressively worsening back pain, lower extremity weakness and numbness concerning for a myelopathic process of uncertain etiology. MRI revealed an epidural soft tissue mass with cord displacement, for which she underwent resection. Histological analysis of the surgical specimen demonstrated CHL. Further investigation revealed an anterior mediastinal mass, consistent with spread from a more typical location.

AB - Classical Hodgkin lymphoma (CHL) commonly arises in lymph nodes and initial presentation with extranodal disease is rare. We report a patient who presented with progressively worsening back pain, lower extremity weakness and numbness concerning for a myelopathic process of uncertain etiology. MRI revealed an epidural soft tissue mass with cord displacement, for which she underwent resection. Histological analysis of the surgical specimen demonstrated CHL. Further investigation revealed an anterior mediastinal mass, consistent with spread from a more typical location.

KW - Epidural cord compression

KW - Hodgkin lymphoma

KW - Spine

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SP - 166

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JO - Journal of Clinical Neuroscience

JF - Journal of Clinical Neuroscience

ER -

Epidural spinal compression as an initial presentation of Hodgkin lymphoma

Abstract

Keywords

ASJC Scopus subject areas

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