TY - JOUR
T1 - Epidermolysis bullosa hereditaria letalis
T2 - PATHOLOGY, NATURAL HISTORY AND THERAPY
AU - SCHACHNER, LAWRENCE
AU - LAZARUS, GERALD S.
AU - DEMBITZER, HERBERT
PY - 1977/1
Y1 - 1977/1
N2 - A patient with epidermolysis bullosa hereditaria letalis had the characteristic electron microscopic lesions not only in the skin, but also in the gastro‐intestinal, genito‐urinary and respiratory tracts. Administration of dexamethasone to this patient resulted in a significant decrease in the blistering. Although the patient died, long term survival in this disease is not rare. We report that staining tissue specimens from patients with epidermolysis bullosa with fluorescein‐labelled bullous pemphigoid antibody is a reliable method for differentiating between junctional and dystrophic disease.
AB - A patient with epidermolysis bullosa hereditaria letalis had the characteristic electron microscopic lesions not only in the skin, but also in the gastro‐intestinal, genito‐urinary and respiratory tracts. Administration of dexamethasone to this patient resulted in a significant decrease in the blistering. Although the patient died, long term survival in this disease is not rare. We report that staining tissue specimens from patients with epidermolysis bullosa with fluorescein‐labelled bullous pemphigoid antibody is a reliable method for differentiating between junctional and dystrophic disease.
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U2 - 10.1111/j.1365-2133.1977.tb05185.x
DO - 10.1111/j.1365-2133.1977.tb05185.x
M3 - Article
C2 - 843437
AN - SCOPUS:0017343385
SN - 0007-0963
VL - 96
SP - 51
EP - 58
JO - British Journal of Dermatology
JF - British Journal of Dermatology
IS - 1
ER -