Epidermal stem cells in Orthopaedic regenerative medicine

Jin Li, Gehua Zhen, Shin Yi Tsai, Xiaofeng Jia

Research output: Contribution to journalArticle

Abstract

In the last decade, great advances have been made in epidermal stem cell studies at the cellular and molecular level. These studies reported various subpopulations and differentiations existing in the epidermal stem cell. Although controversies and unknown issues remain, epidermal stem cells possess an immune-privileged property in transplantation together with easy accessibility, which is favorable for future clinical application. In this review, we will summarize the biological characteristics of epidermal stem cells, and their potential in orthopedic regenerative medicine. Epidermal stem cells play a critical role via cell replacement, and demonstrate significant translational potential in the treatment of orthopedic injuries and diseases, including treatment for wound healing, peripheral nerve and spinal cord injury, and even muscle and bone remodeling.

Original languageEnglish (US)
Pages (from-to)11626-11642
Number of pages17
JournalInternational Journal of Molecular Sciences
Volume14
Issue number6
DOIs
StatePublished - 2013

Fingerprint

orthopedics
Regenerative Medicine
stem cells
Orthopedics
Stem cells
medicine
Stem Cells
spinal cord injuries
wound healing
transplantation
Bone Remodeling
nerves
muscles
Spinal Cord Injuries
Peripheral Nerves
Wound Healing
bones
Muscle
Bone
Transplantation

Keywords

  • Epidermal stem cells
  • Molecular biology
  • Orthopedic regenerative medicine
  • Peripheral nerve injury
  • Spinal cord injury
  • Wound healing

ASJC Scopus subject areas

  • Molecular Biology
  • Computer Science Applications
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Spectroscopy
  • Inorganic Chemistry
  • Catalysis
  • Medicine(all)

Cite this

Epidermal stem cells in Orthopaedic regenerative medicine. / Li, Jin; Zhen, Gehua; Tsai, Shin Yi; Jia, Xiaofeng.

In: International Journal of Molecular Sciences, Vol. 14, No. 6, 2013, p. 11626-11642.

Research output: Contribution to journalArticle

Li, Jin ; Zhen, Gehua ; Tsai, Shin Yi ; Jia, Xiaofeng. / Epidermal stem cells in Orthopaedic regenerative medicine. In: International Journal of Molecular Sciences. 2013 ; Vol. 14, No. 6. pp. 11626-11642.
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