TY - JOUR
T1 - Epidemiology of systemic lupus erythematosus
T2 - An update
AU - Stojan, George
AU - Petri, Michelle
N1 - Publisher Copyright:
Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.
PY - 2018/3/1
Y1 - 2018/3/1
N2 - Purpose of review Systemic lupus erythematosus (SLE) is the prototypical systemic autoimmune disease with a significant disease burden across the world among different ethnic, racial, and age groups. The pathophysiological understanding of SLE is constantly evolving and with it, the need for a better definition of the disease itself, for understanding the risk among the different affected populations, and for identifying the factors responsible for the damage accrual through the years. Recent findings More accurate estimates of incidence and prevalence of SLE among different ethnicities and minority groups not only in the USA, but also in Europe, Middle East, and Asia have provided new insights into the disease burden around the world. Despite advances in treatment, mortality among SLE patients remains high with significant ethnic and geographic variations. Summary Sex, race, and ethnicity significantly affect SLE incidence, prevalence, and mortality.
AB - Purpose of review Systemic lupus erythematosus (SLE) is the prototypical systemic autoimmune disease with a significant disease burden across the world among different ethnic, racial, and age groups. The pathophysiological understanding of SLE is constantly evolving and with it, the need for a better definition of the disease itself, for understanding the risk among the different affected populations, and for identifying the factors responsible for the damage accrual through the years. Recent findings More accurate estimates of incidence and prevalence of SLE among different ethnicities and minority groups not only in the USA, but also in Europe, Middle East, and Asia have provided new insights into the disease burden around the world. Despite advances in treatment, mortality among SLE patients remains high with significant ethnic and geographic variations. Summary Sex, race, and ethnicity significantly affect SLE incidence, prevalence, and mortality.
KW - epidemiology
KW - incidence
KW - mortality
KW - prevalence
KW - systemic lupus erythematosus
UR - http://www.scopus.com/inward/record.url?scp=85042446433&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85042446433&partnerID=8YFLogxK
U2 - 10.1097/BOR.0000000000000480
DO - 10.1097/BOR.0000000000000480
M3 - Review article
C2 - 29251660
AN - SCOPUS:85042446433
SN - 1040-8711
VL - 30
SP - 144
EP - 150
JO - Current opinion in rheumatology
JF - Current opinion in rheumatology
IS - 2
ER -