Epidemiology of ocular chlamydial infection in a trachoma-hyperendemic area

S. K. West, P. Rapoza, B. Munoz, S. Katala, H. R. Taylor

Research output: Contribution to journalArticlepeer-review

Abstract

The epidemiology of ocular chlamydial infection in a trachoma-hyperendemic area of Tanzania was investigated. Specimens for chlamydial isolation cultures and direct fluorescent antibody cytology were collected from 1085 children aged 1-7 years. Other data included examinations for signs of clinical trachoma and the collection of household data on risk factors. A total of 33% of children had a positive laboratory test for Chlamydia species. The most important factors for predicting chlamydial infection were the presence of a sibling with laboratory evidence of infection, increased number of flies around the house, a household that herded cattle, and practice of a local religion. Younger children and girls were at no increased risk for a positive laboratory test, although these subgroups have more clinical disease. The data are compatible with a model of less frequent episodes of reinfection as children become older.

Original languageEnglish (US)
Pages (from-to)752-756
Number of pages5
JournalJournal of Infectious Diseases
Volume163
Issue number4
DOIs
StatePublished - Jan 1 1991

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases

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