Epidemiology of hemolytic-uremic syndrome in Canadian children from 1986 to 1988

Peter Rowe, Elaine Orrbine, George A. Wells, Peter N. McLaine, of the Canadian Pediatric Kidney Disease Reference Centre members of the Canadian Pediatric Kidney Disease Reference Centre

Research output: Contribution to journalArticle

Abstract

Objective: To define the epidemiologic features of childhood hemolytic-uremic syndrome (HUS) on a national level in Canada, to determine the proportion of patients in whom Escherichia coli O157:H7 was isolated from stools, and to examine risk factors for more severe HUS. Design: From January 1986 to December 1988, patients with HUS were reported prospectively to the Canadian Pediatric Kidney Disease Reference Centre, a national registry for pediatric renal disorders, or were identified retrospectively through a medical records search at participating institutions. Setting: All children's hospitals in Canada and the children's wards of general hospitals in Canadian cities with populations greater than 350,000. Patients: Two hundred twenty-six children, including 126 girls. Measurements and main results: The average annual incidence of HUS in children younger than 15 years was 1.44 per 100,000; the peak age-specific incidence was 3.11 per 100,000 younger than 5 years. The incidence of HUS varled by region; the risk of HUS in Alberta was 2.9 times that in Ontario (p

Original languageEnglish (US)
Pages (from-to)218-224
Number of pages7
JournalJournal of Pediatrics
Volume119
Issue number2
DOIs
StatePublished - 1991
Externally publishedYes

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Hemolytic-Uremic Syndrome
Epidemiology
Canada
Incidence
Pediatrics
Alberta
Escherichia coli O157
Kidney Diseases
Ontario
General Hospitals
Medical Records
Registries
Kidney
Population

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Rowe, P., Orrbine, E., Wells, G. A., McLaine, P. N., & members of the Canadian Pediatric Kidney Disease Reference Centre, O. T. C. P. K. D. R. C. (1991). Epidemiology of hemolytic-uremic syndrome in Canadian children from 1986 to 1988. Journal of Pediatrics, 119(2), 218-224. https://doi.org/10.1016/S0022-3476(05)80730-9

Epidemiology of hemolytic-uremic syndrome in Canadian children from 1986 to 1988. / Rowe, Peter; Orrbine, Elaine; Wells, George A.; McLaine, Peter N.; members of the Canadian Pediatric Kidney Disease Reference Centre, of the Canadian Pediatric Kidney Disease Reference Centre.

In: Journal of Pediatrics, Vol. 119, No. 2, 1991, p. 218-224.

Research output: Contribution to journalArticle

Rowe, P, Orrbine, E, Wells, GA, McLaine, PN & members of the Canadian Pediatric Kidney Disease Reference Centre, OTCPKDRC 1991, 'Epidemiology of hemolytic-uremic syndrome in Canadian children from 1986 to 1988', Journal of Pediatrics, vol. 119, no. 2, pp. 218-224. https://doi.org/10.1016/S0022-3476(05)80730-9
Rowe P, Orrbine E, Wells GA, McLaine PN, members of the Canadian Pediatric Kidney Disease Reference Centre OTCPKDRC. Epidemiology of hemolytic-uremic syndrome in Canadian children from 1986 to 1988. Journal of Pediatrics. 1991;119(2):218-224. https://doi.org/10.1016/S0022-3476(05)80730-9
Rowe, Peter ; Orrbine, Elaine ; Wells, George A. ; McLaine, Peter N. ; members of the Canadian Pediatric Kidney Disease Reference Centre, of the Canadian Pediatric Kidney Disease Reference Centre. / Epidemiology of hemolytic-uremic syndrome in Canadian children from 1986 to 1988. In: Journal of Pediatrics. 1991 ; Vol. 119, No. 2. pp. 218-224.
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