TY - JOUR
T1 - Epidemiology of Head and Neck Cancer
AU - Rettig, Eleni
AU - D'Souza, Gypsyamber
N1 - Publisher Copyright:
© 2015 Elsevier Inc.
Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 2015/7/1
Y1 - 2015/7/1
N2 - This article discusses risk factors, incidence trends, and prognostic considerations for head and neck cancer (HNC). The primary causes of HNC are tobacco and alcohol use, and human papillomavirus (HPV). Tobacco-related HNC incidence rates are decreasing in countries where tobacco use has declined. HPV-HNC, which occurs primarily in the oropharynx and is associated with sexual behaviors, has been increasing over the past several decades, among white men in particular. The prognosis for HNC overall has improved slightly since the 1990s, and is influenced by site, stage, and HPV status. Prognosis for HPV-HNC is significantly better than for HPV-negative disease.
AB - This article discusses risk factors, incidence trends, and prognostic considerations for head and neck cancer (HNC). The primary causes of HNC are tobacco and alcohol use, and human papillomavirus (HPV). Tobacco-related HNC incidence rates are decreasing in countries where tobacco use has declined. HPV-HNC, which occurs primarily in the oropharynx and is associated with sexual behaviors, has been increasing over the past several decades, among white men in particular. The prognosis for HNC overall has improved slightly since the 1990s, and is influenced by site, stage, and HPV status. Prognosis for HPV-HNC is significantly better than for HPV-negative disease.
KW - Alcohol
KW - Epidemiology
KW - Head and neck cancer
KW - Human papillomavirus
KW - Tobacco
UR - http://www.scopus.com/inward/record.url?scp=84929504129&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84929504129&partnerID=8YFLogxK
U2 - 10.1016/j.soc.2015.03.001
DO - 10.1016/j.soc.2015.03.001
M3 - Review article
C2 - 25979389
AN - SCOPUS:84929504129
SN - 1055-3207
VL - 24
SP - 379
EP - 396
JO - Surgical Oncology Clinics of North America
JF - Surgical Oncology Clinics of North America
IS - 3
ER -