Epidemiology of autoimmune diseases in Denmark

William W. Eaton; Noel R. Rose; Amanda Kalaydjian; Marianne G. Pedersen; Preben Bo Mortensen

doi:10.1016/j.jaut.2007.05.002

Epidemiology of autoimmune diseases in Denmark

William W. Eaton, Noel R. Rose, Amanda Kalaydjian, Marianne G. Pedersen, Preben Bo Mortensen

Research output: Contribution to journal › Article › peer-review

247 Scopus citations

Abstract

An epidemiologic study of the autoimmune diseases taken together has not been done heretofore. The National Patient Register of Denmark is used to estimate the population prevalence of 31 possible or probable autoimmune diseases. Record linkage is used to estimate 465 pairwise co-morbidities in individuals among the 31 diseases, and familial aggregation among sibs, parents and offspring. The prevalence of any of the 31 diseases in the population is more than 5%. Within individuals, there is extensive comorbidity across the 31 diseases. Within families, aggregation is strongest for individual diseases and weak across diseases. These data confirm the importance of the autoimmune diseases as a group and suggest that common etiopathologies exist among them.

Original language	English (US)
Pages (from-to)	1-9
Number of pages	9
Journal	Journal of Autoimmunity
Volume	29
Issue number	1
DOIs	https://doi.org/10.1016/j.jaut.2007.05.002
State	Published - Aug 2007
Externally published	Yes

Keywords

Autoimmune diseases
Comorbidity
Familial aggregation
Population register
Prevalence
Sex ratio

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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10.1016/j.jaut.2007.05.002

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title = "Epidemiology of autoimmune diseases in Denmark",

abstract = "An epidemiologic study of the autoimmune diseases taken together has not been done heretofore. The National Patient Register of Denmark is used to estimate the population prevalence of 31 possible or probable autoimmune diseases. Record linkage is used to estimate 465 pairwise co-morbidities in individuals among the 31 diseases, and familial aggregation among sibs, parents and offspring. The prevalence of any of the 31 diseases in the population is more than 5%. Within individuals, there is extensive comorbidity across the 31 diseases. Within families, aggregation is strongest for individual diseases and weak across diseases. These data confirm the importance of the autoimmune diseases as a group and suggest that common etiopathologies exist among them.",

keywords = "Autoimmune diseases, Comorbidity, Familial aggregation, Population register, Prevalence, Sex ratio",

author = "Eaton, {William W.} and Rose, {Noel R.} and Amanda Kalaydjian and Pedersen, {Marianne G.} and Mortensen, {Preben Bo}",

note = "Funding Information: This study was supported by an NIMH grant MH53188.",

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T1 - Epidemiology of autoimmune diseases in Denmark

AU - Eaton, William W.

AU - Rose, Noel R.

AU - Kalaydjian, Amanda

AU - Pedersen, Marianne G.

AU - Mortensen, Preben Bo

N1 - Funding Information: This study was supported by an NIMH grant MH53188.

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N2 - An epidemiologic study of the autoimmune diseases taken together has not been done heretofore. The National Patient Register of Denmark is used to estimate the population prevalence of 31 possible or probable autoimmune diseases. Record linkage is used to estimate 465 pairwise co-morbidities in individuals among the 31 diseases, and familial aggregation among sibs, parents and offspring. The prevalence of any of the 31 diseases in the population is more than 5%. Within individuals, there is extensive comorbidity across the 31 diseases. Within families, aggregation is strongest for individual diseases and weak across diseases. These data confirm the importance of the autoimmune diseases as a group and suggest that common etiopathologies exist among them.

AB - An epidemiologic study of the autoimmune diseases taken together has not been done heretofore. The National Patient Register of Denmark is used to estimate the population prevalence of 31 possible or probable autoimmune diseases. Record linkage is used to estimate 465 pairwise co-morbidities in individuals among the 31 diseases, and familial aggregation among sibs, parents and offspring. The prevalence of any of the 31 diseases in the population is more than 5%. Within individuals, there is extensive comorbidity across the 31 diseases. Within families, aggregation is strongest for individual diseases and weak across diseases. These data confirm the importance of the autoimmune diseases as a group and suggest that common etiopathologies exist among them.

KW - Autoimmune diseases

KW - Comorbidity

KW - Familial aggregation

KW - Population register

KW - Prevalence

KW - Sex ratio

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Epidemiology of autoimmune diseases in Denmark

Abstract

Keywords

ASJC Scopus subject areas

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