Epidemiology of autoimmune diseases in Denmark

William W. Eaton, Noel Richard Rose, Amanda Kalaydjian, Marianne G. Pedersen, Preben Bo Mortensen

Research output: Contribution to journalArticlepeer-review


An epidemiologic study of the autoimmune diseases taken together has not been done heretofore. The National Patient Register of Denmark is used to estimate the population prevalence of 31 possible or probable autoimmune diseases. Record linkage is used to estimate 465 pairwise co-morbidities in individuals among the 31 diseases, and familial aggregation among sibs, parents and offspring. The prevalence of any of the 31 diseases in the population is more than 5%. Within individuals, there is extensive comorbidity across the 31 diseases. Within families, aggregation is strongest for individual diseases and weak across diseases. These data confirm the importance of the autoimmune diseases as a group and suggest that common etiopathologies exist among them.

Original languageEnglish (US)
Pages (from-to)1-9
Number of pages9
JournalJournal of Autoimmunity
Issue number1
StatePublished - Aug 2007


  • Autoimmune diseases
  • Comorbidity
  • Familial aggregation
  • Population register
  • Prevalence
  • Sex ratio

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


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