Epidemiology, diagnosis, and treatment of Hymenoptera venom allergy in mastocytosis patients

Marek Niedoszytko; Patrizia Bonadonna; Joanne N.G.Oude Elberink; David B.K. Golden

doi:10.1016/j.iac.2014.02.004

Epidemiology, diagnosis, and treatment of Hymenoptera venom allergy in mastocytosis patients

Marek Niedoszytko, Patrizia Bonadonna, Joanne N.G.Oude Elberink, David B.K. Golden

Johns Hopkins Bayview Hospital

Research output: Contribution to journal › Review article › peer-review

35 Scopus citations

Abstract

Hymenoptera venom allergy is a typical IgE-mediated reaction caused by sensitization to 1 or more allergens of the venom, and accounts for 1.5% to 34% of all cases of anaphylaxis. Patients suffering from mastocytosis are more susceptible to the anaphylactic reactions to an insect sting. This article aims to answer the most important clinical questions raised by the diagnosis and treatment of insect venom allergy in mastocytosis patients. Total avoidance of Hymenoptera is not feasible, and there is no preventive pharmacologic treatment available, although venom immunotherapy reduces the risk of subsequent systemic reactions.

Original language	English (US)
Pages (from-to)	365-381
Number of pages	17
Journal	Immunology and Allergy Clinics of North America
Volume	34
Issue number	2
DOIs	https://doi.org/10.1016/j.iac.2014.02.004
State	Published - May 2014

Keywords

Hymenoptera venom allergy
Immunoglobulin E serology
Mastocytosis
Venom immunotherapy

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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10.1016/j.iac.2014.02.004

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title = "Epidemiology, diagnosis, and treatment of Hymenoptera venom allergy in mastocytosis patients",

abstract = "Hymenoptera venom allergy is a typical IgE-mediated reaction caused by sensitization to 1 or more allergens of the venom, and accounts for 1.5% to 34% of all cases of anaphylaxis. Patients suffering from mastocytosis are more susceptible to the anaphylactic reactions to an insect sting. This article aims to answer the most important clinical questions raised by the diagnosis and treatment of insect venom allergy in mastocytosis patients. Total avoidance of Hymenoptera is not feasible, and there is no preventive pharmacologic treatment available, although venom immunotherapy reduces the risk of subsequent systemic reactions.",

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AU - Golden, David B.K.

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AB - Hymenoptera venom allergy is a typical IgE-mediated reaction caused by sensitization to 1 or more allergens of the venom, and accounts for 1.5% to 34% of all cases of anaphylaxis. Patients suffering from mastocytosis are more susceptible to the anaphylactic reactions to an insect sting. This article aims to answer the most important clinical questions raised by the diagnosis and treatment of insect venom allergy in mastocytosis patients. Total avoidance of Hymenoptera is not feasible, and there is no preventive pharmacologic treatment available, although venom immunotherapy reduces the risk of subsequent systemic reactions.

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Epidemiology, diagnosis, and treatment of Hymenoptera venom allergy in mastocytosis patients

Abstract

Keywords

ASJC Scopus subject areas

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