Epidemiologic characteristics of benign breast disease

Abraham Nomura, George W. Comstock, James A Tonascia

Research output: Contribution to journalArticle

Abstract

To see if the risk factors associated with fibroadenoma and cystic disease were similar to those reported for breast cancer, a retrospective study of benign breast tumor in a general population was conducted in Washington County, Maryland. The study population consisted of 320 white women 20 to 49 years of age who had had benign breast disease and 320 age-matched controls. More cystic disease cases than controls had the following characteristics, which had been reported to have been associated with breast cancer in other studies: higher socioeconomic status; fewer pregnancies; and a lack of association with lactation patterns. Nulliparity, late natural menopause and a maternal history of breast cancer were also more common among cystic cases than controls, although these differences could have occurred by chance. Cystic disease cases and controls did not differ with respect to other factors associated with breast cancer, such as early age at menarche, late age at first pregnancy, and negative history of artificial menopause. In contrast to cystic breast disease, fibroadenoma was not associated with most of the risk factors of breast cancer.

Original languageEnglish (US)
Pages (from-to)505-512
Number of pages8
JournalAmerican Journal of Epidemiology
Volume105
Issue number6
StatePublished - Jun 1977
Externally publishedYes

Fingerprint

Breast Diseases
Breast Neoplasms
Fibroadenoma
Menopause
Fibrocystic Breast Disease
Reproductive History
Menarche
Parity
Lactation
Social Class
Population
Retrospective Studies
Mothers
Pregnancy

Keywords

  • Breast neoplasms
  • Cancer
  • Cysts
  • Fibroma
  • Mastitis
  • Tumors

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Epidemiology

Cite this

Epidemiologic characteristics of benign breast disease. / Nomura, Abraham; Comstock, George W.; Tonascia, James A.

In: American Journal of Epidemiology, Vol. 105, No. 6, 06.1977, p. 505-512.

Research output: Contribution to journalArticle

Nomura, Abraham ; Comstock, George W. ; Tonascia, James A. / Epidemiologic characteristics of benign breast disease. In: American Journal of Epidemiology. 1977 ; Vol. 105, No. 6. pp. 505-512.
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