Environment/Drug-induced Human Autoimmune Disease

J. F. Nyland, Patrizio P Caturegli, N. R. Rose

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Autoimmune diseases comprise a broad spectrum of disorders that share the common basic mechanism of an uncontrolled response to 'self.' While there are some instances where there is a clear genetic predisposition to development of autoimmune disease in humans, for the most part the mechanisms and contributing factors are as complex as the diseases themselves. It seems likely that the greatest proportion of susceptibility to autoimmune disease is due to external, environmental agents, the focus of this chapter. Included in the discussion are environmental agents such as drugs, metals and inorganic compounds, organic compounds, foods, and occupational exposures.

Original languageEnglish (US)
Title of host publicationImmune System Toxicology
PublisherElsevier Inc.
Pages439-453
Number of pages15
Volume5
ISBN (Print)9780080468686
DOIs
StatePublished - Aug 12 2010

Keywords

  • Autoimmune disease
  • Drug-induced
  • Environment
  • Human
  • Inorganic compounds
  • Metals
  • Occupational exposure
  • Organic compounds
  • Xenobiotic

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Nyland, J. F., Caturegli, P. P., & Rose, N. R. (2010). Environment/Drug-induced Human Autoimmune Disease. In Immune System Toxicology (Vol. 5, pp. 439-453). Elsevier Inc.. https://doi.org/10.1016/B978-0-08-046884-6.00625-4