Ensemble dynamics of hippocampal regions CA3 and CA1

John F. Guzowski, James J. Knierim, Edvard I. Moser

Research output: Contribution to journalReview articlepeer-review

Abstract

Computational models based on hippocampal connectivity have proposed that CA3 is uniquely positioned as an autoassociative memory network, capable of performing the competing functions of pattern completion and pattern separation. Recently, three independent studies, two using parallel neurophysiological recording methods and one using immediate-early gene imaging, have examined the responses of CA3 and CA1 ensembles to alterations of environmental context in rats. The results provide converging evidence that CA3 is capable of performing nonlinear transformations of sensory input patterns, whereas CA1 may represent changes in input in a more linear fashion.

Original languageEnglish (US)
Pages (from-to)581-584
Number of pages4
JournalNeuron
Volume44
Issue number4
DOIs
StatePublished - Nov 18 2004

ASJC Scopus subject areas

  • Neuroscience(all)

Fingerprint Dive into the research topics of 'Ensemble dynamics of hippocampal regions CA3 and CA1'. Together they form a unique fingerprint.

Cite this