Enhancing prescription drug innovation and adoption

G. Caleb Alexander, Alec B. O'Connor, Randall S. Stafford

Research output: Contribution to journalArticlepeer-review

Abstract

The adoption and use of a new drug would ideally be guided by its innovation and cost-effectiveness. However, information about the relative efficacy and safety of a drug is typically incomplete even well after market entry, and various other forces create a marketplace in which most new drugs are little better than their older counterparts. Five proposed mechanisms are considered for promoting innovation and reducing the use of therapies ultimately found to offer poor value or have unacceptable risks. These changes range from increasing the evidence required for U.S. Food and Drug Administration approval to modifying the structure of drug reimbursement. Despite the challenges of policy implementation, the United States has a long history of successfully improving the societal value and safe use of prescription medicines.

Original languageEnglish (US)
Pages (from-to)833-837
Number of pages5
JournalAnnals of internal medicine
Volume154
Issue number12
DOIs
StatePublished - Jun 21 2011
Externally publishedYes

ASJC Scopus subject areas

  • Internal Medicine

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