Abstract
Upon differentiation of embryonal carcinoma cells induced by retinoids (10-7 M) the 'apparent' membrane microviscosity increases dramatically. Only biologically active retinoids induce differentiation and cause an enhancement in microviscosity. Several embryonal carcinoma cell lines have a relatively lower 'apparent' microviscosity than their differentiated derivatives, suggesting that this may be a general property of these cells. At higher concentrations retinoids cause a reduction in 'apparent' membrane microviscosity of various cells. This change occurs whether the analogue is biologically active or not, indicating the non-specific nature of this action.
Original language | English (US) |
---|---|
Pages (from-to) | 494-498 |
Number of pages | 5 |
Journal | Experimental cell research |
Volume | 138 |
Issue number | 2 |
DOIs | |
State | Published - Apr 1982 |
Externally published | Yes |
ASJC Scopus subject areas
- Cell Biology