@inproceedings{2a908c4cc978412381236c155829a491,
title = "Enhanced discrimination of calcified and soft arterial plaques using computed tomography with a multi-energy-Window photon counting X-ray detector",
abstract = "This work aims at discriminating between soft and calcified coronary artery plaques using microCT with a multi-energywindow photon counting X-ray detector (PCXD). We have previously investigated a solid state X-ray detector which has the capability to count individual photons in different energy windows. The data from these energy windows may be treated as multiple simultaneous X-ray acquisitions within non-overlapping energy windows that can provide additional information about tissue differences. In this work, we simulated a photon counting detector with five energy windows. We investigated two approaches for using the energy information provided by this detector. First, we applied energy weighting to the reconstruction from different energy windows to improve the signal-to-noise ratio between calcified and soft plaques. This resulted in a significant improvement in the signal-to-noise ratio. Second, we applied the basis material decomposition method to discriminate coronary artery plaques based on their calcium content. The results were compared with those obtained using dual-kVp material decomposition. We observed significantly improved contrast-to-noise ratios for the PCXD-based approaches",
keywords = "Basis material decomposition, Energy weighting, Multi-energy-window photon counting X-ray detector",
author = "Xiaolan Wang and Jingyan Xu and Katsuyuki Taguchi and Frey, {Eric C.} and Patt, {Bradley E.} and Wagenaar, {Douglas J.}",
year = "2009",
doi = "10.1117/12.813877",
language = "English (US)",
isbn = "9780819475091",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Medical Imaging 2009",
note = "Medical Imaging 2009: Physics of Medical Imaging ; Conference date: 09-02-2009 Through 12-02-2009",
}