Endothelial keratoplasty for corneal endothelial dystrophy in a dog

Micki D. Armour, Timothy E. Askew, Allen Eghrari

Research output: Contribution to journalArticle

Abstract

Objective: To assess the efficacy of an endothelial keratoplasty procedure at defined intervals to 1 year postoperatively for the treatment of corneal endothelial dystrophy (CED) in a canine patient. Procedure: A dog diagnosed with CED with progressive corneal edema underwent an endothelial keratoplasty. The patient was examined pre- and postoperatively with slit lamp biomicroscopy and ultrasonic pachymetry. Results: Mean central corneal thickness (CCT) measured with pachymetry was >1400 μm preoperatively and decreased postoperatively to 725 μm. The transplanted donor tissue became transparent 2 weeks postoperatively and incorporated with the recipient cornea. The graft remained transparent throughout the duration of the postoperative period evaluated in this study (2 weeks postoperatively to 1 year). The canine patient was comfortable pre- and postoperatively. Conclusions: Endothelial keratoplasty is a potential therapeutic option for canine cases with progressive corneal thickening due to CED. As this is a single case study, further investigation into the use of endothelial keratoplasty to treat CED is warranted. Moreover, canine patients with CED might serve as a surgical model for human patients with Fuchs’ Endothelial Corneal Dystrophy.

Original languageEnglish (US)
JournalVeterinary Ophthalmology
DOIs
StatePublished - Jan 1 2019

Keywords

  • canine
  • corneal endothelial dystrophy
  • Fuchs’ endothelial corneal dystrophy

ASJC Scopus subject areas

  • veterinary(all)

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