Endoscopic treatment of Crohn's complications

Andrea Buda, Patrick I. Okolo

Research output: Contribution to journalReview article

Abstract

The progression to fistula and strictures is part of the natural history of Crohn's disease (CD) and these complications negatively affect the quality of life of CD patients. Surgery is the traditional treatment of CD strictures. However, due the chronicity of the inflammatory process and the associated fibrosis, postoperative recurrence occurs frequently. The lack of specific drug to treat fibrotic strictures and their irreversible nature has drawn the attention to less invasive and bowel-sparing therapeutic modalities. Endoluminal therapies may provide effective option in relieving symptoms associated with CD complications and reduce the need for repeated surgery with substantial clinical benefit. This review will discuss the current use and efficacy of the endoscopic treatment of CD complications. New endoscopic modalities and recent advances will be also evaluated.

Original languageEnglish (US)
Pages (from-to)887-895
Number of pages9
JournalExpert Review of Gastroenterology and Hepatology
Volume8
Issue number8
DOIs
StatePublished - Nov 1 2014

Keywords

  • Crohn's disease
  • Endoscopic balloon dilation
  • Fistula
  • Stent positioning
  • Strictures

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

Fingerprint Dive into the research topics of 'Endoscopic treatment of Crohn's complications'. Together they form a unique fingerprint.

  • Cite this