TY - JOUR
T1 - Endoscopic mucosa-sparing lateral dissection for treatment of gastric submucosal tumors
T2 - A prospective cohort study
AU - Li, Yue
AU - Zhang, Qiang
AU - Zhu, Chaojun
AU - Luo, Yuchen
AU - Han, Zelong
AU - Qing, Haitao
AU - Cai, Jianqun
AU - Li, Ling
AU - Huang, Ying
AU - Liu, Side
N1 - Funding Information:
The authors acknowledge support from the following institutions: Guangdong Province Universities and Colleges Pearl River Scholar Funded Scheme; Guangzhou Pilot Project of Clinical and Translational Research Center (early gastrointestinal can- cers, No.7415696196402); and Guangdong Provincial Bio-engineering Research Center for Gastroenterology Diseases.
Publisher Copyright:
© Georg Thieme Verlag KG Stuttgart New York.
PY - 2018/5/16
Y1 - 2018/5/16
N2 - Background, In our previous work, we developed a modified method for the removal of gastric submucosal tumors (SMTs), called endoscopic mucosa-sparing lateral dissection (EMSLD). This prospective study aimed to evaluate the efficacy and postoperative outcomes of EMSLD. Methods, We prospectively enrolled 25 consecutive patients with gastric SMTs, who received EMSLD treatment. Clinicopathological characteristics and operation-related outcomes were analyzed. Results, The mean age of patients was 49.3 ± 9.7 years, and the mean tumor size was 14.6 ± 6.1 mm. En bloc resection was achieved in all cases. The mean procedure time was 47.3 ± 25.9 minutes, and the estimated blood loss was 4.8 ± 3.5 mL. Endoscopic full-thickness resection was performed in six patients (24 %) because the tumors originated from the deep muscularis propria layer. All perforations and resection defects were successfully closed by the retained mucosa and endoclips. No serious complications related to EMSLD were encountered during or after the procedure. Conclusions, EMSLD was reliable and effective for the removal of gastric SMTs. However, large-scale randomized controlled trials are needed.
AB - Background, In our previous work, we developed a modified method for the removal of gastric submucosal tumors (SMTs), called endoscopic mucosa-sparing lateral dissection (EMSLD). This prospective study aimed to evaluate the efficacy and postoperative outcomes of EMSLD. Methods, We prospectively enrolled 25 consecutive patients with gastric SMTs, who received EMSLD treatment. Clinicopathological characteristics and operation-related outcomes were analyzed. Results, The mean age of patients was 49.3 ± 9.7 years, and the mean tumor size was 14.6 ± 6.1 mm. En bloc resection was achieved in all cases. The mean procedure time was 47.3 ± 25.9 minutes, and the estimated blood loss was 4.8 ± 3.5 mL. Endoscopic full-thickness resection was performed in six patients (24 %) because the tumors originated from the deep muscularis propria layer. All perforations and resection defects were successfully closed by the retained mucosa and endoclips. No serious complications related to EMSLD were encountered during or after the procedure. Conclusions, EMSLD was reliable and effective for the removal of gastric SMTs. However, large-scale randomized controlled trials are needed.
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U2 - 10.1055/a-0603-3761
DO - 10.1055/a-0603-3761
M3 - Article
C2 - 29768644
AN - SCOPUS:85047107290
SN - 0013-726X
VL - 50
SP - 886
EP - 890
JO - Endoscopy
JF - Endoscopy
IS - 9
ER -