Endoscopic mucosa-sparing lateral dissection for treatment of gastric submucosal tumors: A prospective cohort study

Yue Li, Qiang Zhang, Chaojun Zhu, Yuchen Luo, Zelong Han, Haitao Qing, Jianqun Cai, Ling Li, Ying Huang, Side Liu

Research output: Contribution to journalArticle

Abstract

Background, In our previous work, we developed a modified method for the removal of gastric submucosal tumors (SMTs), called endoscopic mucosa-sparing lateral dissection (EMSLD). This prospective study aimed to evaluate the efficacy and postoperative outcomes of EMSLD. Methods, We prospectively enrolled 25 consecutive patients with gastric SMTs, who received EMSLD treatment. Clinicopathological characteristics and operation-related outcomes were analyzed. Results, The mean age of patients was 49.3 ± 9.7 years, and the mean tumor size was 14.6 ± 6.1 mm. En bloc resection was achieved in all cases. The mean procedure time was 47.3 ± 25.9 minutes, and the estimated blood loss was 4.8 ± 3.5 mL. Endoscopic full-thickness resection was performed in six patients (24 %) because the tumors originated from the deep muscularis propria layer. All perforations and resection defects were successfully closed by the retained mucosa and endoclips. No serious complications related to EMSLD were encountered during or after the procedure. Conclusions, EMSLD was reliable and effective for the removal of gastric SMTs. However, large-scale randomized controlled trials are needed.

Original languageEnglish (US)
Pages (from-to)886-890
Number of pages5
JournalEndoscopy
Volume50
Issue number9
DOIs
StatePublished - May 16 2018

ASJC Scopus subject areas

  • Gastroenterology

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    Li, Y., Zhang, Q., Zhu, C., Luo, Y., Han, Z., Qing, H., Cai, J., Li, L., Huang, Y., & Liu, S. (2018). Endoscopic mucosa-sparing lateral dissection for treatment of gastric submucosal tumors: A prospective cohort study. Endoscopy, 50(9), 886-890. https://doi.org/10.1055/a-0603-3761