Endoscopic localization and tattooing of a proinsulinoma for minimally invasive resection

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10 Scopus citations


Hypoglycemia can be common in patients using insulin injections or certain antidiabetes medications. In rare cases, hypoglycemia can be caused by a pancreatic insulinoma. We report a case of a 33-year-old woman found to have severe recurrent hypoglycemia. Diagnostic studies such as continuous glucose monitoring and a hospitalized fast provided biochemical evidence for a proinsulinoma. After abdominal multidetector contrast-enhanced computerized tomography failed to detect pancreatic abnormalities, endoscopic ultrasonography identified and localized a 9-mm pancreatic tail lesion. At the time of endoscopy, the lesion was tattooed with ultrasonographic guidance for subsequent laparoscopic visualization and curative resection.

Original languageEnglish (US)
Pages (from-to)474-477
Number of pages4
Issue number3
StatePublished - Apr 1 2011


  • endoscopic ultrasound
  • hypoglycemia
  • insulinoma
  • laparascopy
  • proinsulinoma

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Hepatology
  • Endocrinology


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