Endoscopic endonasal versus transcranial approach to resection of olfactory groove meningiomas: a systematic review

Aarti Purohit, Roshani Jha, Adham M. Khalafallah, Carrie Price, Nicholas R. Rowan, Debraj Mukherjee

Research output: Contribution to journalReview articlepeer-review

Abstract

Despite the increasing utility of the endoscopic endonasal approach (EEA) for management of anterior skull base (ASB) pathologies, the optimal treatment strategy for olfactory groove meningiomas (OGM) remains unclear. This project sought to systematically compare outcomes of EEA management with conventional transcranial approach (TCA) for the treatment of OGMs. A systematic review was performed to identify studies that compared outcomes following EEA and TCA for OGMs. Data extracted from each study included gross total resection (GTR), incidence of cerebrospinal fluid (CSF) leaks, and post-operative complications including anosmia. The results of the search yielded 5 studies which met the criteria for inclusion and analysis. All studies compared TCA (n = 922) with EEA (n = 141) outcomes for OGMs. Overall, the rate of gross total resection (GTR) was lower among the endoscopic group (70.9%) relative to the transcranial group (91.5%). The rate of post-operative CSF leak was 6.3% vs. 25.5% for the transcranial and endoscopic groups, respectively. Post-operative anosmia was higher for patients undergoing EEA (95.9%) compared with patients in the transcranial group (37.4%). In this analysis, EEA was associated with a lower rate of GTR and higher incidences of CSF leaks and post-operative anosmia. However, with increasing surgeon familiarity of the endoscopic anatomy and technique for managing ASB pathologies, a nuanced approach may be used to minimize patient morbidity and widen the spectrum of skull base surgery.

Original languageEnglish (US)
Pages (from-to)1465-1471
Number of pages7
JournalNeurosurgical Review
Volume43
Issue number6
DOIs
StatePublished - Dec 2020

Keywords

  • Craniotomy
  • Endoscopy
  • Meningioma
  • Olfactory groove
  • Skull base

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Endoscopic endonasal versus transcranial approach to resection of olfactory groove meningiomas: a systematic review'. Together they form a unique fingerprint.

Cite this