Endometriosis-associated invasive adenocarcinoma involving the rectum in a postmenopausal female: Report of a case

Adrian M. Moran, Jane W. Newburger, Stephen P. Sanders, Ira A. Parness, Philip J. Spevak, Jane C. Burns, Steven D. Colan

Research output: Contribution to journalArticlepeer-review

Abstract

Sampson first reported a case of malignant transformation of endometriosis to adenocarcinoma in 1925. We present a case of such transformation occurring in a postmenopausal female 22 years after total abdominal hysterectomy and bilateral salpingo-oophorectomy. This case demonstrates histologic progression from endometriosis to complex hyperplasia with cytologic atypia, and ultimately to invasive endometrioid adenocarcinoma involving the rectum. Aggressive surgical extirpation of all visible colorectal endometriosis for patients with advanced disease is recommended.

Original languageEnglish (US)
Pages (from-to)1530-1533
Number of pages4
JournalDiseases of the colon and rectum
Volume44
Issue number10
DOIs
StatePublished - 2001

Keywords

  • Adenocarcinoma
  • Endometriosis
  • Hyperplasia
  • Rectum

ASJC Scopus subject areas

  • Gastroenterology

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