Endocrine treatment of transsexual people: A review of treatment regimens, outcomes, and adverse effects

Eva Moore, Amy Wisniewski, Adrian Dobs

Research output: Contribution to journalReview articlepeer-review

Abstract

Cross-sex hormone treatment is an important component in medical treatment of transsexual people. Endocrinologists are often faced with designing treatment recommendations. Although guidelines from organizations, such as the Harry Benjamin International Gender Dysphoria Association, have been helpful, management remains complex and experience guided. We discuss the range of treatment used by transsexual people, the rationale behind these, and the expectation from such treatment. Recommendations from seven clinical research centers treating transsexual people are discussed. In addition, self-reported hormonal regimens from 25 male-to-female transsexual people and five female-to-male transsexual people are reported. Finally, the potential adverse effects of cross-sex hormone treatment of transsexual people are reviewed. In light of the complexity of managing treatment goals and adverse effects, the active involvement of a medical doctor experienced in cross-sex hormonal therapy is vital to ensure the safety of transsexual people.

Original languageEnglish (US)
Pages (from-to)3467-3473
Number of pages7
JournalJournal of Clinical Endocrinology and Metabolism
Volume88
Issue number8
DOIs
StatePublished - Aug 1 2003

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Endocrinology
  • Clinical Biochemistry
  • Biochemistry, medical

Fingerprint Dive into the research topics of 'Endocrine treatment of transsexual people: A review of treatment regimens, outcomes, and adverse effects'. Together they form a unique fingerprint.

Cite this