Endocrine neoplasia in New World primates

José L.C. Dias, Richard J. Montali, John D. Strandberg, Linda K. Johnson, Michael J. Wolff

Research output: Contribution to journalArticlepeer-review


Of 1,106 New World primates necropsied from the National Zoological Park (Washington, D.C.) and the Department of Comparative Pathology, Johns Hopkins University School of Medicine (Baltimore, Maryland) 22 (1.9%) animals were identified with 27 neoplasms. Of this group, nine animals (two females, seven males) had a total of 13 endocrine neoplasms. All animals were adults, with an age range of 2.7-25 years (average, 12.1 years). Seven were Callitrichidae and two were Cebidae. The adrenal gland was the most affected organ, with seven (53.8%) neoplasms, followed by the pituitary and thyroid gland with two (15.4%) cases each, and the pancreas and parathyroid gland with one tumor (7.7%) each. All neoplastic disorders were benign. Immunocytochemistry assays for growth hormone, adrenocorticotropic hormone, prolactin, follicle-stimulating hormone, luteinizing hormone, thyroid-stimulating hormone, and chromogranin A were performed on two pituitary neoplasms. Pheochromocytoma was the most frequent neoplasm, representing 5 (38.4%) of the 13 neoplasms. The remaining were thyroid cystadenoma (two, 15.4%), corticotrophic cell pituitary adenoma (two, 15.4%), adrenal ganglioneuroma (one, 7.7%), adrenal cortical adenoma (one, 7.7%), parathyroid chief-cell adenoma (one, 7.7%), and pancreatic islet-cell adenoma (one, 7.7%).

Original languageEnglish (US)
Pages (from-to)34-41
Number of pages8
JournalJournal of Medical Primatology
Issue number1
StatePublished - Jan 1996


  • Callitrichidae
  • Cebidae
  • Monkey
  • Pheochromocytoma
  • Pituitary tumor
  • Platyrrhini

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)


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