Application of hormone assays to the monitoring of high-risk pregnancies is most helpful if the assays are performed serially in any one patient to offset marked intraindividual and interindividual biological variability. The problem of clinically defining and identifying abnormal fetal conditions, such as intrauterine growth retardation, makes the correlation between clinical outcomes and laboratory tests difficult. As a result, most hormone tests do not yield optimal sensitivity and specificity. These assays have thus been adjuncts to other diagnostic procedures in clinical decision-making.
|Original language||English (US)|
|Number of pages||23|
|Journal||Clinics in laboratory medicine|
|State||Published - 1981|
ASJC Scopus subject areas
- Clinical Biochemistry
- Biochemistry, medical