Endobronchial Pseudallescheria boydii in lung transplant patient with cystic fibrosis

Sonia S. Shah, Demet Karnak, Marie Budev, Robin K. Avery, Atul C. Mehta

Research output: Contribution to journalArticle

Abstract

Emerging fungal pathogens in immunocompromised patients have recently challenged physicians. Aspergillus spp., Coccidioides immitis, Zygomycetes, Candida spp., and Cryptococcus neoformans are the most common fungal pathogens causing endobronchial involvement, with Aspergillus being by far the most common endobronchial pathogen in lung transplant recipients. Scedosporium spp. are considered emerging fungal pathogens and include 2 main human pathogens namely S. apiospermum, the asexual state of Pseudallescheria boydii (P. boydii), and S. prolificans. Both these species may cause disseminated infection, which is associated with high mortality. We present a dramatic bronchoscopic image of P. boydii endobronchial infection after lung transplantation in a patient with underlying cystic fibrosis. P. boydii should be in the differential diagnosis of endobronchial infections in patients with cystic fibrosis receiving lung transplantation.

Original languageEnglish (US)
Pages (from-to)48-50
Number of pages3
JournalJournal of Bronchology
Volume14
Issue number1
DOIs
StatePublished - Jan 1 2007
Externally publishedYes

Keywords

  • Cystic fibrosis
  • Endobronchial
  • Lung transplantation
  • Pseudallescheria boydii
  • Scedosporium spp.

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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