Endemic Burkitt Lymphoma in second-degree relatives in Northern Uganda: in-depth genome-wide analysis suggests clues about genetic susceptibility

Mateus H. Gouveia; Isaac Otim; Martin D. Ogwang; Mingyi Wang; Bin Zhu; Nathan Cole; Wen Luo; Belynda Hicks; Kristine Jones; Kathrin Oehl-Huber; Leona W. Ayers; Stefania Pittaluga; Ismail D. Legason; Hadijah Nabalende; Patrick Kerchan; Tobias Kinyera; Esther Kawira; Glen Brubaker; Arthur G. Levin; Lutz Guertler; Jung Kim; Douglas R. Stewart; Melissa Adde; Ian Magrath; Andrew W. Bergen; Steven J. Reynolds; Meredith Yeager; Kishor Bhatia; Adebowale A. Adeyemo; Ludmila Prokunina-Olsson; Michael Dean; Daniel Shriner; Charles N. Rotimi; Stephen Chanock; Reiner Siebert; Sam M. Mbulaiteye

doi:10.1038/s41375-020-01052-w

Endemic Burkitt Lymphoma in second-degree relatives in Northern Uganda: in-depth genome-wide analysis suggests clues about genetic susceptibility

Mateus H. Gouveia, Isaac Otim, Martin D. Ogwang, Mingyi Wang, Bin Zhu, Nathan Cole, Wen Luo, Belynda Hicks, Kristine Jones, Kathrin Oehl-Huber, Leona W. Ayers, Stefania Pittaluga, Ismail D. Legason, Hadijah Nabalende, Patrick Kerchan, Tobias Kinyera, Esther Kawira, Glen Brubaker, Arthur G. Levin, Lutz GuertlerJung Kim, Douglas R. Stewart, Melissa Adde, Ian Magrath, Andrew W. Bergen, Steven J. Reynolds, Meredith Yeager, Kishor Bhatia, Adebowale A. Adeyemo, Ludmila Prokunina-Olsson, Michael Dean, Daniel Shriner, Charles N. Rotimi, Stephen Chanock, Reiner Siebert, Sam M. Mbulaiteye

Research output: Contribution to journal › Article › peer-review

Original language	English (US)
Pages (from-to)	1209-1213
Number of pages	5
Journal	Leukemia
Volume	35
Issue number	4
DOIs	https://doi.org/10.1038/s41375-020-01052-w
State	Published - Apr 2021
Externally published	Yes

ASJC Scopus subject areas

Hematology
Oncology
Cancer Research

Access to Document

10.1038/s41375-020-01052-w

Cite this

Gouveia, M. H., Otim, I., Ogwang, M. D., Wang, M., Zhu, B., Cole, N., Luo, W., Hicks, B., Jones, K., Oehl-Huber, K., Ayers, L. W., Pittaluga, S., Legason, I. D., Nabalende, H., Kerchan, P., Kinyera, T., Kawira, E., Brubaker, G., Levin, A. G., ... Mbulaiteye, S. M. (2021). Endemic Burkitt Lymphoma in second-degree relatives in Northern Uganda: in-depth genome-wide analysis suggests clues about genetic susceptibility. Leukemia, 35(4), 1209-1213. https://doi.org/10.1038/s41375-020-01052-w

Gouveia, MH, Otim, I, Ogwang, MD, Wang, M, Zhu, B, Cole, N, Luo, W, Hicks, B, Jones, K, Oehl-Huber, K, Ayers, LW, Pittaluga, S, Legason, ID, Nabalende, H, Kerchan, P, Kinyera, T, Kawira, E, Brubaker, G, Levin, AG, Guertler, L, Kim, J, Stewart, DR, Adde, M, Magrath, I, Bergen, AW, Reynolds, SJ, Yeager, M, Bhatia, K, Adeyemo, AA, Prokunina-Olsson, L, Dean, M, Shriner, D, Rotimi, CN, Chanock, S, Siebert, R & Mbulaiteye, SM 2021, 'Endemic Burkitt Lymphoma in second-degree relatives in Northern Uganda: in-depth genome-wide analysis suggests clues about genetic susceptibility', Leukemia, vol. 35, no. 4, pp. 1209-1213. https://doi.org/10.1038/s41375-020-01052-w

@article{6900c02e860c46d0bd2072df43a74645,

title = "Endemic Burkitt Lymphoma in second-degree relatives in Northern Uganda: in-depth genome-wide analysis suggests clues about genetic susceptibility",

author = "Gouveia, {Mateus H.} and Isaac Otim and Ogwang, {Martin D.} and Mingyi Wang and Bin Zhu and Nathan Cole and Wen Luo and Belynda Hicks and Kristine Jones and Kathrin Oehl-Huber and Ayers, {Leona W.} and Stefania Pittaluga and Legason, {Ismail D.} and Hadijah Nabalende and Patrick Kerchan and Tobias Kinyera and Esther Kawira and Glen Brubaker and Levin, {Arthur G.} and Lutz Guertler and Jung Kim and Stewart, {Douglas R.} and Melissa Adde and Ian Magrath and Bergen, {Andrew W.} and Reynolds, {Steven J.} and Meredith Yeager and Kishor Bhatia and Adeyemo, {Adebowale A.} and Ludmila Prokunina-Olsson and Michael Dean and Daniel Shriner and Rotimi, {Charles N.} and Stephen Chanock and Reiner Siebert and Mbulaiteye, {Sam M.}",

note = "Funding Information: Acknowledgements We thank the study subjects for their participation. We thank Dr. Joseph Fraumeni Jr, former Director of the Division of Cancer Epidemiology and Genetics (DCEG) at National Cancer Institute (NCI), for his support and scientific guidance while conducting this study. We thank Ms. Janet Lawler-Heavner at Westat Inc. (Rockville, MD, USA) and Mr. Erisa Sunday at the African Field Epidemiology Network (Kampala, Uganda) for managing the study. We thank Ms. Laurie Buck, Dr. Carol Giffen, and Mr. Greg Rydzak at Information Management Services Inc. (Calverton, MD, USA) for preparing data analysis files. We thank the members of the tumor genetic group at the Institute of Human Genetics for expert technical assistance and fruitful discussions and Josef H{\"o}gel for support with CADD score evaluation. The study was funded by the Intramural",

year = "2021",

month = apr,

doi = "10.1038/s41375-020-01052-w",

language = "English (US)",

volume = "35",

pages = "1209--1213",

journal = "Leukemia",

issn = "0887-6924",

publisher = "Nature Publishing Group",

number = "4",

}

TY - JOUR

T1 - Endemic Burkitt Lymphoma in second-degree relatives in Northern Uganda

T2 - in-depth genome-wide analysis suggests clues about genetic susceptibility

AU - Gouveia, Mateus H.

AU - Otim, Isaac

AU - Ogwang, Martin D.

AU - Wang, Mingyi

AU - Zhu, Bin

AU - Cole, Nathan

AU - Luo, Wen

AU - Hicks, Belynda

AU - Jones, Kristine

AU - Oehl-Huber, Kathrin

AU - Ayers, Leona W.

AU - Pittaluga, Stefania

AU - Legason, Ismail D.

AU - Nabalende, Hadijah

AU - Kerchan, Patrick

AU - Kinyera, Tobias

AU - Kawira, Esther

AU - Brubaker, Glen

AU - Levin, Arthur G.

AU - Guertler, Lutz

AU - Kim, Jung

AU - Stewart, Douglas R.

AU - Adde, Melissa

AU - Magrath, Ian

AU - Bergen, Andrew W.

AU - Reynolds, Steven J.

AU - Yeager, Meredith

AU - Bhatia, Kishor

AU - Adeyemo, Adebowale A.

AU - Prokunina-Olsson, Ludmila

AU - Dean, Michael

AU - Shriner, Daniel

AU - Rotimi, Charles N.

AU - Chanock, Stephen

AU - Siebert, Reiner

AU - Mbulaiteye, Sam M.

N1 - Funding Information: Acknowledgements We thank the study subjects for their participation. We thank Dr. Joseph Fraumeni Jr, former Director of the Division of Cancer Epidemiology and Genetics (DCEG) at National Cancer Institute (NCI), for his support and scientific guidance while conducting this study. We thank Ms. Janet Lawler-Heavner at Westat Inc. (Rockville, MD, USA) and Mr. Erisa Sunday at the African Field Epidemiology Network (Kampala, Uganda) for managing the study. We thank Ms. Laurie Buck, Dr. Carol Giffen, and Mr. Greg Rydzak at Information Management Services Inc. (Calverton, MD, USA) for preparing data analysis files. We thank the members of the tumor genetic group at the Institute of Human Genetics for expert technical assistance and fruitful discussions and Josef Högel for support with CADD score evaluation. The study was funded by the Intramural

PY - 2021/4

Y1 - 2021/4

UR - http://www.scopus.com/inward/record.url?scp=85092479594&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85092479594&partnerID=8YFLogxK

U2 - 10.1038/s41375-020-01052-w

DO - 10.1038/s41375-020-01052-w

M3 - Article

C2 - 33051549

AN - SCOPUS:85092479594

VL - 35

SP - 1209

EP - 1213

JO - Leukemia

JF - Leukemia

SN - 0887-6924

IS - 4

ER -

Endemic Burkitt Lymphoma in second-degree relatives in Northern Uganda: in-depth genome-wide analysis suggests clues about genetic susceptibility

ASJC Scopus subject areas

Access to Document

Other files and links

Cite this