End-stage renal disease and African American race are independent predictors of mild liver fibrosis in patients with chronic hepatitis C infection

Florence M. Aslinia, S. K. Wasan, A. L. Mindikoglu, O. A. Adeyemo, Benjamin Philosophe, C. Drachenberg, C. D. Howell

Research output: Contribution to journalArticle

Abstract

Recipients of haemodialysis for end-stage renal disease (ESRD) have a higher prevalence of hepatitis C virus (HCV) infection relative to the general US population. However, the natural course of HCV infection in patients with renal failure, including African Americans (AAs) and Caucasian Americans (CAs), is not well known. We compared the degree of liver inflammation and fibrosis in AA and CA patients with HCV infection, with and without ESRD. This was a cross-sectional study of 156 HCV patients with ESRD (130 AAs and 26 CAs) with a liver biopsy between 1992 and 2005. The control group consisted of 138 patients (50 AAs; 88 CAs) with HCV infections and a serum creatinine

Original languageEnglish (US)
Pages (from-to)371-376
Number of pages6
JournalJournal of Viral Hepatitis
Volume19
Issue number5
DOIs
StatePublished - May 2012
Externally publishedYes

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Keywords

  • Cirrhosis
  • End-stage renal disease
  • Hepatitis C
  • Liver fibrosis

ASJC Scopus subject areas

  • Hepatology
  • Infectious Diseases
  • Virology

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