Enabling [18F]-bicyclo[6.1.0]nonyne for oligonucleotide conjugation for positron emission tomography applications: [18F]-anti-microRNA-21 as an example

Xiang Guo Li, Anne Roivainen, Jörgen Bergman, Arttu Heinonen, Frank Bengel, Thomas Thum, Juhani Knuuti

Research output: Contribution to journalArticle

Abstract

A bicyclononyne-based prosthetic group has been developed for 18F-labeling of anti-microRNA-21, an oligonucleotide, in a near-stoichiometric manner.

Original languageEnglish (US)
Pages (from-to)9821-9824
Number of pages4
JournalChemical Communications
Volume51
Issue number48
DOIs
StatePublished - Jun 18 2015

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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