Enabling migration by moderation: YAP/TAZ are essential for persistent migration

Praful R. Nair, Denis Wirtz

Research output: Contribution to journalShort surveypeer-review

Abstract

Persistent cell migration plays a crucial role in physiological processes, but its underlying mechanisms of regulation remain unclear. Mason et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201806065) show that YAP/TAZ limit cytoskeletal tension, which is essential for persistent (but not initiation of) cell migration. Potential implications of this study range from embryonic development to metastasis.

Original languageEnglish (US)
Pages (from-to)1092-1093
Number of pages2
JournalJournal of Cell Biology
Volume218
Issue number4
DOIs
StatePublished - Apr 1 2019

ASJC Scopus subject areas

  • Cell Biology

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