Emerging therapies for food allergy

Research output: Contribution to journalReview articlepeer-review

Abstract

Food allergy is a common condition for which there are currently no approved treatments except avoidance of the allergenic food and treatment of accidental reactions. There are several potential treatments that are under active investigation in animal and human studies, but it is not yet clear what the best approach may be. Here, we review approaches that are currently in clinical trials, including oral, sublingual, and epicutaneous immunotherapy, immunotherapy combined with anti-IgE, and Chinese herbal medicine as well as approaches that are in preclinical or early clinical investigation, including modified protein immunotherapy, adjuvants, DNA vaccines, and helminth administration. We discuss the importance of fully exploring the risks and benefits of any treatment before it is taken to general clinical practice and the need for clarity about the goals of treatment.

Original languageEnglish (US)
Pages (from-to)1880-1886
Number of pages7
JournalJournal of Clinical Investigation
Volume124
Issue number5
DOIs
StatePublished - 2014

ASJC Scopus subject areas

  • Medicine(all)

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