Emerging strategies for cancer immunoprevention

J. C. Roeser, S. D. Leach, F. McAllister

Research output: Contribution to journalReview article

Abstract

The crucial role of the immune system in the formation and progression of tumors has been widely accepted. On one hand, the surveillance role of the immune system plays an important role in endogenous tumor prevention, but on the other hand, in some special circumstances such as in chronic inflammation, the immune system can actually contribute to the formation and progression of tumors. In recent years, there has been an explosion of novel targeted immunotherapies for advanced cancers. In the present manuscript, we explore known and potential various types of cancer prevention strategies and focus on nonvaccine-based cancer preventive strategies targeting the immune system at the early stages of tumorigenesis.

Original languageEnglish (US)
Pages (from-to)6029-6039
Number of pages11
JournalOncogene
Volume34
Issue number50
DOIs
StatePublished - Dec 10 2015

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research

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  • Cite this

    Roeser, J. C., Leach, S. D., & McAllister, F. (2015). Emerging strategies for cancer immunoprevention. Oncogene, 34(50), 6029-6039. https://doi.org/10.1038/onc.2015.98