Emerging role of intensity-modulated radiation therapy in anorectal cancer

Jeffrey Meyer, Christopher G. Willett, Brian G. Czito

Research output: Contribution to journalReview article

Abstract

Although radiation therapy has an established role to play in the management of rectal and anal tumors, there are often treatment-related morbidities that negatively impact on patients. There is a long-standing interest in radiation oncology on maximizing treatment efficacy while minimizing treatment-related toxicities, which can be pronounced in the treatment of pelvic malignancies. Intensity-modulated radiation therapy is a recently introduced technology that has the potential to increase the efficacy:toxicity ratio. It has been implemented in the treatment of prostate and head and neck tumors with success. This article reviews the rationale for its use in treating anorectal tumors and discusses early clinical data supporting its continued investigation.

Original languageEnglish (US)
Pages (from-to)585-593
Number of pages9
JournalExpert Review of Anticancer Therapy
Volume8
Issue number4
DOIs
StatePublished - Apr 1 2008
Externally publishedYes

Fingerprint

Radiotherapy
Neoplasms
Radiation Oncology
Therapeutics
Rectal Neoplasms
Prostate
Neck
Head
Technology
Morbidity

Keywords

  • IMRT
  • Intensity-modulated radiation therapy
  • Radiation
  • Rectum
  • Tolerance
  • Toxicity

ASJC Scopus subject areas

  • Oncology
  • Pharmacology (medical)

Cite this

Emerging role of intensity-modulated radiation therapy in anorectal cancer. / Meyer, Jeffrey; Willett, Christopher G.; Czito, Brian G.

In: Expert Review of Anticancer Therapy, Vol. 8, No. 4, 01.04.2008, p. 585-593.

Research output: Contribution to journalReview article

Meyer, Jeffrey ; Willett, Christopher G. ; Czito, Brian G. / Emerging role of intensity-modulated radiation therapy in anorectal cancer. In: Expert Review of Anticancer Therapy. 2008 ; Vol. 8, No. 4. pp. 585-593.
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