Emerging role for the cytoskeleton as an organizer and regulator of translation

Seyun Kim, Pierre A. Coulombe

Research output: Contribution to journalReview articlepeer-review

Abstract

The cytoskeleton is an intricate and dynamic fibrous network that has an essential role in the generation and regulation of cell architecture and cellular mechanical properties. The cytoskeleton also evolved as a scaffold that supports diverse biochemical pathways. Recent evidence favours the hypothesis that the cytoskeleton participates in the spatial organization and regulation of translation, at both the global and local level, in a manner that is crucial for cellular growth, proliferation and function.

Original languageEnglish (US)
Pages (from-to)75-81
Number of pages7
JournalNature Reviews Molecular Cell Biology
Volume11
Issue number1
DOIs
StatePublished - Jan 1 2010

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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