Emerging fungal infections in solid organ transplant recipients

Research output: Contribution to journalReview article

Abstract

The most important emerging and rare fungal pathogens in solid organ transplant recipients are the Zygomycetes, Scedosporium, Fusarium, and the dark molds. Factors affecting the emergence of these fungi include the combination of intensive immunosuppressive regimens with increasingly widespread use of long-term azole antifungal therapy; employment of aggressive diagnostic approaches (eg, sampling of bronchoalveolar lavage fluid); and changes in patients' interactions with the environment. This article reviews the epidemiology, microbiology, and clinical impact of emerging fungal infections in solid organ transplant recipients, and provides up-to-date recommendations on their treatment.

Original languageEnglish (US)
Pages (from-to)305-316
Number of pages12
JournalInfectious disease clinics of North America
Volume27
Issue number2
DOIs
StatePublished - Jun 1 2013

Keywords

  • Fusarium
  • Scedosporium
  • Solid organ transplant
  • Zygomycetes

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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