TY - JOUR
T1 - Emerging cancer-targeted therapies
AU - Arceci, Robert J.
AU - Cripe, Timothy P.
PY - 2002/12/1
Y1 - 2002/12/1
N2 - There is reason to believe that the unfolding revolution in molecular biology and translational research will allow selective targeting of tumor cells, and radically change the way general practitioners and pediatric oncologists treat and follow children with cancer. This article highlights some of the most promising approaches being tested in the field. By learning about the underlying biology, the remaining hurdles, the projected timeline, and the possible impact of new therapies on the practice of pediatric oncology, health care professionals and patients should be better prepared for the future of pediatric oncology.
AB - There is reason to believe that the unfolding revolution in molecular biology and translational research will allow selective targeting of tumor cells, and radically change the way general practitioners and pediatric oncologists treat and follow children with cancer. This article highlights some of the most promising approaches being tested in the field. By learning about the underlying biology, the remaining hurdles, the projected timeline, and the possible impact of new therapies on the practice of pediatric oncology, health care professionals and patients should be better prepared for the future of pediatric oncology.
UR - http://www.scopus.com/inward/record.url?scp=0036976417&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036976417&partnerID=8YFLogxK
U2 - 10.1016/S0031-3955(02)00096-2
DO - 10.1016/S0031-3955(02)00096-2
M3 - Review article
C2 - 12580369
AN - SCOPUS:0036976417
VL - 49
SP - 1339
EP - 1368
JO - Pediatric Clinics of North America
JF - Pediatric Clinics of North America
SN - 0031-3955
IS - 6
ER -