Embryonal cell carcinoma of the ovary: Report of a case

W. Delano Meriwether, H. E. Ramsey, S. P. Ward

Research output: Contribution to journalArticle

Abstract

An adolescent girl with embryonal cell carcinoma of the ovary was treated with surgery and a new combination of chemothera-peutic drugs-5-fluorouracil, cytoxan, methotrexate, and vincristine. Her survival of 15 months was unusual for this highly malignant gonadal tumor. Histopathologically at autopsy, her embryonal cell carcinoma featured a characteristic network of spaces lined with embryonal cells, as well as distinctive glomerulus-like structures, and hyaline bodies located intracellularly and extracellularly. Continued investigation and further clinical trial with surgery and combination chemotherapy is warranted in an effort to manage highly malignant embryonal cell carcinoma of the ovary.

Original languageEnglish (US)
Pages (from-to)497-504
Number of pages8
JournalOncology
Volume25
Issue number6
DOIs
StatePublished - 1971
Externally publishedYes

Fingerprint

Embryonal Carcinoma Stem Cells
Ovary
Hyalin
Vincristine
Combination Drug Therapy
Methotrexate
Fluorouracil
Cyclophosphamide
Autopsy
Clinical Trials
Survival
Pharmaceutical Preparations
Neoplasms

Keywords

  • Carcinoma
  • Chemotherapy
  • Embryonal

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Meriwether, W. D., Ramsey, H. E., & Ward, S. P. (1971). Embryonal cell carcinoma of the ovary: Report of a case. Oncology, 25(6), 497-504. https://doi.org/10.1159/000224600

Embryonal cell carcinoma of the ovary : Report of a case. / Meriwether, W. Delano; Ramsey, H. E.; Ward, S. P.

In: Oncology, Vol. 25, No. 6, 1971, p. 497-504.

Research output: Contribution to journalArticle

Meriwether, WD, Ramsey, HE & Ward, SP 1971, 'Embryonal cell carcinoma of the ovary: Report of a case', Oncology, vol. 25, no. 6, pp. 497-504. https://doi.org/10.1159/000224600
Meriwether, W. Delano ; Ramsey, H. E. ; Ward, S. P. / Embryonal cell carcinoma of the ovary : Report of a case. In: Oncology. 1971 ; Vol. 25, No. 6. pp. 497-504.
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