EM-navigated catheter placement for gynecologic brachytherapy: An accuracy study

Alireza Mehrtash, Antonio Damato, Guillaume Pernelle, Lauren Barber, Nabgha Farhat, Akila Viswanathan, Robert Cormack, Tina Kapur

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Gynecologic malignancies, including cervical, endometrial, ovarian, vaginal and vulvar cancers, cause significant mortality in women worldwide. The standard care for many primary and recurrent gynecologic cancers consists of chemoradiation followed by brachytherapy. In high dose rate (HDR) brachytherapy, intracavitary applicators and/or interstitial needles are placed directly inside the cancerous tissue so as to provide catheters to deliver high doses of radiation. Although technology for the navigation of catheters and needles is well developed for procedures such as prostate biopsy, brain biopsy, and cardiac ablation, it is notably lacking for gynecologic HDR brachytherapy. Using a benchtop study that closely mimics the clinical interstitial gynecologic brachytherapy procedure, we developed a method for evaluating the accuracy of image-guided catheter placement. Future bedside translation of this technology offers the potential benefit of maximizing tumor coverage during catheter placement while avoiding damage to the adjacent organs, for example bladder, rectum and bowel. In the study, two independent experiments were performed on a phantom model to evaluate the targeting accuracy of an electromagnetic (EM) tracking system. The procedure was carried out using a laptop computer (2.1GHz Intel Core i7 computer, 8GB RAM, Windows 7 64-bit), an EM Aurora tracking system with a 1.3mm diameter 6 DOF sensor, and 6F (2 mm) brachytherapy catheters inserted through a Syed-Neblett applicator. The 3D Slicer and PLUS open source software were used to develop the system. The mean of the targeting error was less than 2.9mm, which is comparable to the targeting errors in commercial clinical navigation systems.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2014: Image-Guided Procedures, Robotic Interventions, and Modeling
PublisherSPIE
Volume9036
ISBN (Print)9780819498298
DOIs
StatePublished - 2014
Externally publishedYes
EventMedical Imaging 2014: Image-Guided Procedures, Robotic Interventions, and Modeling - San Diego, CA, United States
Duration: Feb 18 2014Feb 20 2014

Other

OtherMedical Imaging 2014: Image-Guided Procedures, Robotic Interventions, and Modeling
CountryUnited States
CitySan Diego, CA
Period2/18/142/20/14

Fingerprint

Catheters
Electromagnetic Phenomena
Brachytherapy
electromagnetism
navigation
needles
dosage
interstitials
cancer
Applicators
Biopsy
rectum
bladder
mortality
Needles
organs
ablation
Point-of-Care Systems
brain
Vaginal Neoplasms

Keywords

  • catheter placement
  • electromagnetic tracking
  • gynecologic brachytherapy
  • image-guided therapy
  • radiation therapy

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Mehrtash, A., Damato, A., Pernelle, G., Barber, L., Farhat, N., Viswanathan, A., ... Kapur, T. (2014). EM-navigated catheter placement for gynecologic brachytherapy: An accuracy study. In Medical Imaging 2014: Image-Guided Procedures, Robotic Interventions, and Modeling (Vol. 9036). [90361F] SPIE. https://doi.org/10.1117/12.2044381

EM-navigated catheter placement for gynecologic brachytherapy : An accuracy study. / Mehrtash, Alireza; Damato, Antonio; Pernelle, Guillaume; Barber, Lauren; Farhat, Nabgha; Viswanathan, Akila; Cormack, Robert; Kapur, Tina.

Medical Imaging 2014: Image-Guided Procedures, Robotic Interventions, and Modeling. Vol. 9036 SPIE, 2014. 90361F.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Mehrtash, A, Damato, A, Pernelle, G, Barber, L, Farhat, N, Viswanathan, A, Cormack, R & Kapur, T 2014, EM-navigated catheter placement for gynecologic brachytherapy: An accuracy study. in Medical Imaging 2014: Image-Guided Procedures, Robotic Interventions, and Modeling. vol. 9036, 90361F, SPIE, Medical Imaging 2014: Image-Guided Procedures, Robotic Interventions, and Modeling, San Diego, CA, United States, 2/18/14. https://doi.org/10.1117/12.2044381
Mehrtash A, Damato A, Pernelle G, Barber L, Farhat N, Viswanathan A et al. EM-navigated catheter placement for gynecologic brachytherapy: An accuracy study. In Medical Imaging 2014: Image-Guided Procedures, Robotic Interventions, and Modeling. Vol. 9036. SPIE. 2014. 90361F https://doi.org/10.1117/12.2044381
Mehrtash, Alireza ; Damato, Antonio ; Pernelle, Guillaume ; Barber, Lauren ; Farhat, Nabgha ; Viswanathan, Akila ; Cormack, Robert ; Kapur, Tina. / EM-navigated catheter placement for gynecologic brachytherapy : An accuracy study. Medical Imaging 2014: Image-Guided Procedures, Robotic Interventions, and Modeling. Vol. 9036 SPIE, 2014.
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