Elevated urinary prostaglandins and the effect of aspirin on renal function in lupus erythematosus

R. P. Kimberly, J. R. Gill, R. E. Bowden, H. R. Keiser, P. H. Plotz

Research output: Contribution to journalArticlepeer-review

Abstract

We studied the urinary excretion of immunoreactive prostaglandin E-like material (iPGE) and renal function in 7 women with systemic lupus erythematosus to evaluate the relation between urinary iPGE and the increase in serum creatinine in patients taking aspirin. The mean pretreatment excretion of urinary iPGE in patients with lupus erythematosus, 42.7 ± 6.4 ng/h, was significantly higher than the value of 29.0 ± 1.9 ng/h for normal subjects (P

Original languageEnglish (US)
Pages (from-to)336-341
Number of pages6
JournalAnnals of Internal Medicine
Volume89
Issue number3
StatePublished - 1978
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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