Elevated plasma testosterone and gonadotropin levels in infertile males with hyperthyroidism

H. R. Clyde, P. C. Walsh, R. W. English

Research output: Contribution to journalArticlepeer-review

42 Scopus citations


Little attention has been given to the existence of male infertility in hyperthyroidism and the mechanisms adversely affecting spermatogenesis therein. The chance presentation of three young thyrotoxic men within a short period of time allowed us to document the common findings in all three of reversibly impaired semen quality. The unexpected finding of elevated testosterone and gonadotropin levels in each case, with return of these values to normal on attaining euthyroidism, and the finding of maturation arrest in one patient prior to treatment of his thyrotoxicosis, allow some considerations of the altered physiology and spermatogenic defect and suggest a need for further attention to this disorder.

Original languageEnglish (US)
Pages (from-to)662-666
Number of pages5
JournalFertility and sterility
Issue number6
StatePublished - 1976
Externally publishedYes

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology


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