Elevated medial-frontal cerebral blood flow in obsessive-compulsive patients: A SPECT study

Steven R. Machlin; Gordon J. Harris; Godfrey D. Pearlson; Rudolf Hoehn-Saric; Petra Jeffery; Edwaldo E. Camargo

doi:10.1176/ajp.148.9.1240

Elevated medial-frontal cerebral blood flow in obsessive-compulsive patients: A SPECT study

Steven R. Machlin, Gordon J. Harris, Godfrey D. Pearlson, Rudolf Hoehn-Saric, Petra Jeffery, Edwaldo E. Camargo

Research output: Contribution to journal › Article › peer-review

166 Scopus citations

Abstract

Regional cerebral blood flow was measured with single photon emission computed tomography in 10 obsessive-compulsive patients and eight comparison subjects. The patients had a significantly higher ratio of medial-frontal to whole cortex blood flow; this was unrelated to symptom severity but was correlated negatively with anxiety. No differences in orbital-frontal blood flow were found.

Original language	English (US)
Pages (from-to)	1240-1242
Number of pages	3
Journal	American Journal of Psychiatry
Volume	148
Issue number	9
DOIs	https://doi.org/10.1176/ajp.148.9.1240
State	Published - 1991
Externally published	Yes

ASJC Scopus subject areas

Psychiatry and Mental health

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10.1176/ajp.148.9.1240

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abstract = "Regional cerebral blood flow was measured with single photon emission computed tomography in 10 obsessive-compulsive patients and eight comparison subjects. The patients had a significantly higher ratio of medial-frontal to whole cortex blood flow; this was unrelated to symptom severity but was correlated negatively with anxiety. No differences in orbital-frontal blood flow were found.",

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year = "1991",

doi = "10.1176/ajp.148.9.1240",

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AU - Machlin, Steven R.

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AU - Hoehn-Saric, Rudolf

AU - Jeffery, Petra

AU - Camargo, Edwaldo E.

PY - 1991

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AB - Regional cerebral blood flow was measured with single photon emission computed tomography in 10 obsessive-compulsive patients and eight comparison subjects. The patients had a significantly higher ratio of medial-frontal to whole cortex blood flow; this was unrelated to symptom severity but was correlated negatively with anxiety. No differences in orbital-frontal blood flow were found.

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Elevated medial-frontal cerebral blood flow in obsessive-compulsive patients: A SPECT study

Abstract

ASJC Scopus subject areas

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