Elevated medial-frontal cerebral blood flow in obsessive-compulsive patients: A SPECT study

Steven R. Machlin, Gordon J. Harris, Godfrey D. Pearlson, Rudolf Hoehn-Saric, Petra Jeffery, Edwaldo E. Camargo

Research output: Contribution to journalArticlepeer-review

Abstract

Regional cerebral blood flow was measured with single photon emission computed tomography in 10 obsessive-compulsive patients and eight comparison subjects. The patients had a significantly higher ratio of medial-frontal to whole cortex blood flow; this was unrelated to symptom severity but was correlated negatively with anxiety. No differences in orbital-frontal blood flow were found.

Original languageEnglish (US)
Pages (from-to)1240-1242
Number of pages3
JournalAmerican Journal of Psychiatry
Volume148
Issue number9
DOIs
StatePublished - 1991
Externally publishedYes

ASJC Scopus subject areas

  • Psychiatry and Mental health

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