Elevated medial-frontal cerebral blood flow in obsessive-compulsive patients: A SPECT study

Steven R. Machlin, Gordon J. Harris, Godfrey D. Pearlson, Rudolf Hoehn-Saric, Petra Jeffery, Edwaldo E. Camargo

Research output: Contribution to journalArticle

Abstract

Regional cerebral blood flow was measured with single photon emission computed tomography in 10 obsessive-compulsive patients and eight comparison subjects. The patients had a significantly higher ratio of medial-frontal to whole cortex blood flow; this was unrelated to symptom severity but was correlated negatively with anxiety. No differences in orbital-frontal blood flow were found.

Original languageEnglish (US)
Pages (from-to)1240-1242
Number of pages3
JournalAmerican Journal of Psychiatry
Volume148
Issue number9
StatePublished - 1991
Externally publishedYes

Fingerprint

Cerebrovascular Circulation
Single-Photon Emission-Computed Tomography
Regional Blood Flow
Anxiety

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Machlin, S. R., Harris, G. J., Pearlson, G. D., Hoehn-Saric, R., Jeffery, P., & Camargo, E. E. (1991). Elevated medial-frontal cerebral blood flow in obsessive-compulsive patients: A SPECT study. American Journal of Psychiatry, 148(9), 1240-1242.

Elevated medial-frontal cerebral blood flow in obsessive-compulsive patients : A SPECT study. / Machlin, Steven R.; Harris, Gordon J.; Pearlson, Godfrey D.; Hoehn-Saric, Rudolf; Jeffery, Petra; Camargo, Edwaldo E.

In: American Journal of Psychiatry, Vol. 148, No. 9, 1991, p. 1240-1242.

Research output: Contribution to journalArticle

Machlin, SR, Harris, GJ, Pearlson, GD, Hoehn-Saric, R, Jeffery, P & Camargo, EE 1991, 'Elevated medial-frontal cerebral blood flow in obsessive-compulsive patients: A SPECT study', American Journal of Psychiatry, vol. 148, no. 9, pp. 1240-1242.
Machlin, Steven R. ; Harris, Gordon J. ; Pearlson, Godfrey D. ; Hoehn-Saric, Rudolf ; Jeffery, Petra ; Camargo, Edwaldo E. / Elevated medial-frontal cerebral blood flow in obsessive-compulsive patients : A SPECT study. In: American Journal of Psychiatry. 1991 ; Vol. 148, No. 9. pp. 1240-1242.
@article{1086a6807622478d82f05cd0e453eec6,
title = "Elevated medial-frontal cerebral blood flow in obsessive-compulsive patients: A SPECT study",
abstract = "Regional cerebral blood flow was measured with single photon emission computed tomography in 10 obsessive-compulsive patients and eight comparison subjects. The patients had a significantly higher ratio of medial-frontal to whole cortex blood flow; this was unrelated to symptom severity but was correlated negatively with anxiety. No differences in orbital-frontal blood flow were found.",
author = "Machlin, {Steven R.} and Harris, {Gordon J.} and Pearlson, {Godfrey D.} and Rudolf Hoehn-Saric and Petra Jeffery and Camargo, {Edwaldo E.}",
year = "1991",
language = "English (US)",
volume = "148",
pages = "1240--1242",
journal = "American Journal of Psychiatry",
issn = "0002-953X",
publisher = "American Psychiatric Association",
number = "9",

}

TY - JOUR

T1 - Elevated medial-frontal cerebral blood flow in obsessive-compulsive patients

T2 - A SPECT study

AU - Machlin, Steven R.

AU - Harris, Gordon J.

AU - Pearlson, Godfrey D.

AU - Hoehn-Saric, Rudolf

AU - Jeffery, Petra

AU - Camargo, Edwaldo E.

PY - 1991

Y1 - 1991

N2 - Regional cerebral blood flow was measured with single photon emission computed tomography in 10 obsessive-compulsive patients and eight comparison subjects. The patients had a significantly higher ratio of medial-frontal to whole cortex blood flow; this was unrelated to symptom severity but was correlated negatively with anxiety. No differences in orbital-frontal blood flow were found.

AB - Regional cerebral blood flow was measured with single photon emission computed tomography in 10 obsessive-compulsive patients and eight comparison subjects. The patients had a significantly higher ratio of medial-frontal to whole cortex blood flow; this was unrelated to symptom severity but was correlated negatively with anxiety. No differences in orbital-frontal blood flow were found.

UR - http://www.scopus.com/inward/record.url?scp=0025850414&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025850414&partnerID=8YFLogxK

M3 - Article

C2 - 1883006

AN - SCOPUS:0025850414

VL - 148

SP - 1240

EP - 1242

JO - American Journal of Psychiatry

JF - American Journal of Psychiatry

SN - 0002-953X

IS - 9

ER -