Elevated levels of circulating soluble adhesion molecules in peripheral blood of patients with unstable angina

Nitin K. Ghaisas, Chandreshwar N. Shahi, Brendan Foley, Michael Goggins, Peter Crean, Alan Kelly, Dermot Kelleher, Michael Walsh

Research output: Contribution to journalArticlepeer-review

Abstract

We have demonstrated increased levels of the circulating soluble adhesion molecules (sCAMs), ICAM-1, VCAM-1, and E-selectin in patients with unstable angina compared with healthy controls. Our findings support the role of inflammation in clinically unstable coronary disease, and may indicate a potential role for measurement of peripheral sICAM levels as a marker for inflammatory activity in atherosclerotic plaque.

Original languageEnglish (US)
Pages (from-to)617-619
Number of pages3
JournalAmerican Journal of Cardiology
Volume80
Issue number5
DOIs
StatePublished - Sep 1 1997
Externally publishedYes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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