Elevated levels of circulating soluble adhesion molecules in peripheral blood of patients with unstable angina

Nitin K. Ghaisas, Chandreshwar N. Shahi, Brendan Foley, Michael S Goggins, Peter Crean, Alan Kelly, Dermot Kelleher, Michael Walsh

Research output: Contribution to journalArticle

Abstract

We have demonstrated increased levels of the circulating soluble adhesion molecules (sCAMs), ICAM-1, VCAM-1, and E-selectin in patients with unstable angina compared with healthy controls. Our findings support the role of inflammation in clinically unstable coronary disease, and may indicate a potential role for measurement of peripheral sICAM levels as a marker for inflammatory activity in atherosclerotic plaque.

Original languageEnglish (US)
Pages (from-to)617-618
Number of pages2
JournalThe American Journal of Cardiology
Volume80
Issue number5
DOIs
StatePublished - Sep 1 1997
Externally publishedYes

Fingerprint

E-Selectin
Vascular Cell Adhesion Molecule-1
Unstable Angina
Atherosclerotic Plaques
Intercellular Adhesion Molecule-1
Coronary Disease
Inflammation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Elevated levels of circulating soluble adhesion molecules in peripheral blood of patients with unstable angina. / Ghaisas, Nitin K.; Shahi, Chandreshwar N.; Foley, Brendan; Goggins, Michael S; Crean, Peter; Kelly, Alan; Kelleher, Dermot; Walsh, Michael.

In: The American Journal of Cardiology, Vol. 80, No. 5, 01.09.1997, p. 617-618.

Research output: Contribution to journalArticle

Ghaisas, Nitin K. ; Shahi, Chandreshwar N. ; Foley, Brendan ; Goggins, Michael S ; Crean, Peter ; Kelly, Alan ; Kelleher, Dermot ; Walsh, Michael. / Elevated levels of circulating soluble adhesion molecules in peripheral blood of patients with unstable angina. In: The American Journal of Cardiology. 1997 ; Vol. 80, No. 5. pp. 617-618.
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