Elevated levels of circulating soluble adhesion molecules in patients with nonrheumatic aortic stenosis

Chandreshwar N. Shahi, Nitin K. Ghaisas, Michael Goggins, Brendan Foley, Peter Crean, Dermot Kelleher, Michael Walsh

Research output: Contribution to journalArticlepeer-review

Abstract

Increased serum levels of soluble adhesion molecules are found in various disorders of inflammatory or immunologic etiology. We found elevated levels of the soluble adhesion molecules ICAM-1, VCAM-1, and E-selectin in patients with nonrheumatic aortic stenosis, suggesting that inflammation may be important in the pathogenesis of this condition, which is generally believed to be degenerative.

Original languageEnglish (US)
Pages (from-to)980-982
Number of pages3
JournalAmerican Journal of Cardiology
Volume79
Issue number7
DOIs
StatePublished - Apr 1 1997
Externally publishedYes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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