Elevated high-sensitivity c-reactive protein as a risk marker of the attenuated relationship between serum cholesterol and cardiovascular events at older age

Seamus Whelton, Probal Roy, Brad C. Astor, Lin Zhang, Ron C. Hoogeveen, Christie M. Ballantyne, Josef Coresh

Research output: Contribution to journalArticle

Abstract

The relationship between cholesterol and coronary heart disease (CHD) is attenuated at older age. We analyzed cholesterol level as a predictor of CHD in 8,947 participants from the Atherosclerosis Risk in Communities (ARIC) Study, a large multicenter cohort study that enrolled participants in 1987-1989 at 4 field centers in Washington County, Maryland; Forsyth County, North Carolina; Jackson, Mississippi; and Minneapolis, Minnesota. Participants in the present analysis had no history of CHD and were stratified by age (

Original languageEnglish (US)
Pages (from-to)1076-1084
Number of pages9
JournalAmerican Journal of Epidemiology
Volume178
Issue number7
DOIs
StatePublished - Oct 1 2013

Fingerprint

Coronary Disease
Cholesterol
Serum
Mississippi
Proteins
Multicenter Studies
Atherosclerosis
Cohort Studies

Keywords

  • C-reactive protein
  • elderly persons
  • serum cholesterol

ASJC Scopus subject areas

  • Epidemiology

Cite this

Elevated high-sensitivity c-reactive protein as a risk marker of the attenuated relationship between serum cholesterol and cardiovascular events at older age. / Whelton, Seamus; Roy, Probal; Astor, Brad C.; Zhang, Lin; Hoogeveen, Ron C.; Ballantyne, Christie M.; Coresh, Josef.

In: American Journal of Epidemiology, Vol. 178, No. 7, 01.10.2013, p. 1076-1084.

Research output: Contribution to journalArticle

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