Elevated aspartate aminotransferase-to-platelet ratio index in perinatally HIV-infected children in the United States

George K. Siberry, Kunjal Patel, Jorge A. Pinto, Ana Puga, Ayesha Mirza, Tracie L. Miller, Russell B. Van Dyke

Research output: Contribution to journalArticle

Abstract

Elevated aspartate aminotransferase-to-platelet ratio index may signal liver fibrosis. Among 397 US children with perinatal HIV infection, at baseline was >1.5 in 0.8% [95% confidence interval (CI), 0.2-2.2%) and >0.5 in 6.5% (95% CI, 4.3-9.4%); incidence on study was 0.5 (95% CI, 0.2-1.2) and 6.4 (95% CI, 4.8-8.3) per 100 person-years, respectively. Longterm liver outcomes after perinatal HIV infection warrant further study.

Original languageEnglish (US)
Pages (from-to)855-857
Number of pages3
JournalPediatric Infectious Disease Journal
Volume33
Issue number8
DOIs
StatePublished - Aug 2014

Keywords

  • APRI
  • HIV
  • Liver

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)
  • Infectious Diseases

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