Elephant endotheliotropic herpesvirus hemorrhagic disease in asian elephant calves in Logging Camps, Myanmar

Zaw Min Oo, Ye Htut Aung, Tin Tun Aung, Nyo San, Zaw Min Tun, Gary S. Hayward, Arun Zachariah

Research output: Contribution to journalArticle


In recent years, an alarming number of cases of lethal acute hemorrhagic disease have occurred in Asian elephant calves raised in logging camps in Myanmar. To determine whether these deaths were associated with infection by elephant endotheliotropic herpesvirus (EEHV), we conducted diagnostic PCR subtype DNA sequencing analysis on necropsy tissue samples collected from 3 locations. We found that EEHV DNA from 7 PCR loci was present at high levels in all 3 calves and was the same EEHV1A virus type that has been described in North America, Europe, and other parts of Asia. However, when analyzed over 5,610 bp, the strains showed major differences from each other and from all previously characterized EEHV1A strains. We conclude that these 3 elephant calves in Myanmar died from the same herpesvirus disease that has afflicted young Asian elephants in other countries over the past 20 years.

Original languageEnglish (US)
Pages (from-to)63-69
Number of pages7
JournalEmerging infectious diseases
Issue number1
StatePublished - Jan 1 2020


ASJC Scopus subject areas

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases

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