Electrophysiologic models of heart cells and cell networks

Enabling a better understanding of arrhythmias and heart disease

Nitish V Thakor, Jose M. Ferrero, Javier Saiz, Boris Gramatikov, Jose M. Ferrero

Research output: Contribution to journalArticle

Abstract

The availability of various experimental techniques to study cardiac cell electrophysiological properties has enabled the formulation of mathematical models of the electrical behavior of excitable cells. These models have been used extensively in cardiac electrophysiology because of their ability to simulate in precise detail the electrical events that take place across the cell membrane. They provide a desirable alternative for exploring the basic electrophysiological mechanisms in normal and abnormal cells. The basic principles of action potential modeling are discussed and the development of cellular models of normal and diseased cells is reviewed.

Original languageEnglish (US)
Pages (from-to)73-83
Number of pages11
JournalIEEE Engineering in Medicine and Biology Magazine
Volume17
Issue number5
DOIs
StatePublished - Sep 1998

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Cardiac Arrhythmias
Heart Diseases
Cell membranes
Cells
Cardiac Electrophysiology
Availability
Mathematical models
Action Potentials
Theoretical Models
Cell Membrane

ASJC Scopus subject areas

  • Biomedical Engineering
  • Health Informatics
  • Health Information Management

Cite this

Electrophysiologic models of heart cells and cell networks : Enabling a better understanding of arrhythmias and heart disease. / Thakor, Nitish V; Ferrero, Jose M.; Saiz, Javier; Gramatikov, Boris; Ferrero, Jose M.

In: IEEE Engineering in Medicine and Biology Magazine, Vol. 17, No. 5, 09.1998, p. 73-83.

Research output: Contribution to journalArticle

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