Electrophysiologic features of fibular neuropathy in childhood and adolescence

Ioannis Karakis, Mohammed Khoshnoodi, Wendy Liew, Elizabeth S. Nguyen, H. Royden Jones, Basil T. Darras, Peter B. Kang

Research output: Contribution to journalArticle

Abstract

Introduction: We studied patterns of nerve injury in pediatric common fibular (peroneal) neuropathy (CFN). Methods: A retrospective analysis was performed on data from 53 children with CFN at a pediatric electromyography laboratory. Results: Conduction block at the fibular head was present in 35% of patients. Deep fibular axonal loss was identified in 77%, while superficial fibular axonal loss was identified in 45%. The pathophysiology was predominantly axonal in 72%, mostly demyelinating in 6%, and mixed in 22%. Predominantly demyelinating lesions at the fibular head demonstrated sparing of the superficial fibular sensory nerve (P = 0.01, Fischer exact test). Predominantly axonal lesions had a moderate correlation between superficial and deep fibular axonal loss (Spearman r = 0.52; P = 0.0001). Conclusions: There is frequent axonal and fascicular injury in pediatric CFN, similar to adults. Deep and superficial fibular nerve involvements correlate in axonal lesions, whereas superficial fibular sensory fibers are often spared in demyelinating lesions. Muscle Nerve, 2016 Muscle Nerve 55: 693–697, 2017.

Original languageEnglish (US)
Pages (from-to)693-697
Number of pages5
JournalMuscle and Nerve
Volume55
Issue number5
DOIs
StatePublished - May 1 2017

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Peroneal Neuropathies
Peroneal Nerve
Pediatrics
Head
Muscles
Wounds and Injuries
Electromyography

Keywords

  • clinical neurophysiology
  • common fibular nerve
  • common fibular neuropathy
  • common peroneal neuropathy
  • electrodiagnosis
  • electromyography (EMG)
  • pediatric EMG

ASJC Scopus subject areas

  • Physiology
  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Physiology (medical)

Cite this

Karakis, I., Khoshnoodi, M., Liew, W., Nguyen, E. S., Jones, H. R., Darras, B. T., & Kang, P. B. (2017). Electrophysiologic features of fibular neuropathy in childhood and adolescence. Muscle and Nerve, 55(5), 693-697. https://doi.org/10.1002/mus.25403

Electrophysiologic features of fibular neuropathy in childhood and adolescence. / Karakis, Ioannis; Khoshnoodi, Mohammed; Liew, Wendy; Nguyen, Elizabeth S.; Jones, H. Royden; Darras, Basil T.; Kang, Peter B.

In: Muscle and Nerve, Vol. 55, No. 5, 01.05.2017, p. 693-697.

Research output: Contribution to journalArticle

Karakis, I, Khoshnoodi, M, Liew, W, Nguyen, ES, Jones, HR, Darras, BT & Kang, PB 2017, 'Electrophysiologic features of fibular neuropathy in childhood and adolescence', Muscle and Nerve, vol. 55, no. 5, pp. 693-697. https://doi.org/10.1002/mus.25403
Karakis, Ioannis ; Khoshnoodi, Mohammed ; Liew, Wendy ; Nguyen, Elizabeth S. ; Jones, H. Royden ; Darras, Basil T. ; Kang, Peter B. / Electrophysiologic features of fibular neuropathy in childhood and adolescence. In: Muscle and Nerve. 2017 ; Vol. 55, No. 5. pp. 693-697.
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